Bioenergetics and Brain Health 4: Brain Aging, Alzheimer’s and Parkinson’s Diseases, and Stroke

In this final episode of the Bioenergetics and Brain Health series I talk about changes that occur in brain cells during normal aging, and in Alzheimer’s disease, Parkinson’s disease, and stroke with emphasis on alterations upstream and downstream of cellular energy metabolism. The episode concludes with examples of therapeutic interventions that target those age- and disease-related alterations. 

LINKS:

Hallmarks of Brain Aging

https://pmc.ncbi.nlm.nih.gov/articles/PMC6039826/pdf/nihms979409.pdf

Brain Energy Rescue:

https://pmc.ncbi.nlm.nih.gov/articles/PMC7948516/pdf/nihms-1624328.pdf

The Hormesis Principle of Brain Health and Resilience

https://pmc.ncbi.nlm.nih.gov/articles/PMC5209274/pdf/nihms834422.pdf