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Blood transfusions and quality of life in MDS [MDS Patient & Family Report]

May 1, 2023
Prof. Rena Buckstein, a leading hematology expert from Toronto, joins Prof. Moshe Mittelman to explore blood transfusions' critical role in managing myelodysplastic syndromes (MDS). They discuss the importance of personalized transfusion strategies tailored to individual health needs and hemoglobin levels. The conversation delves into the risks of iron overload from repeated transfusions and the benefits of iron chelation therapy. They aim to clarify misconceptions about transfusion limits and focus on enhancing the quality of life for MDS patients.
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INSIGHT

Vital Role of RBC Transfusions

  • Red blood cell transfusions are life-saving for MDS patients with symptomatic anemia.
  • They improve oxygen delivery and day-to-day functioning but don't change disease course.
ADVICE

Manage Risks for Long-term Transfusions

  • Patients can receive red blood cell transfusions indefinitely if risks are managed.
  • Manage risks like iron overload and circulatory issues using diuretics and iron chelation.
ADVICE

Individualize Transfusion Thresholds

  • Personalize hemoglobin thresholds for transfusions based on patient's symptoms and function.
  • Work with your physician to identify when you feel debilitated and use that for transfusion timing.
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