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Exercise scientist Dr. Nick Tiller joins Neil deGrasse Tyson, Chuck Nice, and Gary O’Reilly on StarTalk Radio to discuss the science behind weight loss drugs, off-label prescriptions, and the ethics of Ozempic use. Topics covered include the FDA approval of Osempic for type 2 diabetes, the potential effects of weight loss drugs on dementia and Alzheimer's, managing inflammation for better health, and the availability and demand for a popular drug.
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Quick takeaways
- Semaglutide, a GLP1 agonist, is an effective weight loss drug that also helps control blood sugar levels in individuals with type 2 diabetes.
- Semaglutide is a synthetic form of the hormone GLP1, originally discovered in lizard venom, and has a half-life of five to seven days.
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Semaglutide's Effectiveness in Weight Loss and Blood Sugar Control
Semaglutide, a GLP1 agonist, has proven to be effective in helping individuals lose weight and control blood sugar levels. Clinical trials have shown an average weight loss of 15% of body weight, which is clinically meaningful. It works by suppressing appetite, slowing gastric emptying, and reducing glucose production. Not only is semaglutide effective for weight loss, but it is also just as good, if not better, than insulin in controlling blood sugar levels in individuals with type 2 diabetes.
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