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Precision medicine in oncology, exemplified by the cancer drug Keytruda, showcases a paradigm shift in cancer treatment. Keytruda's unique approach targets specific cancer types by unleashing the immune system's ability to identify and eliminate cancer cells, contrasting chemotherapy's broader effects. While Keytruda demonstrates significant efficacy, it also poses challenges, such as limited effectiveness against all cancer types and potential side effects, urging a multifaceted treatment approach.