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The Paul Taylor Podcast
Wisdom Wednesdays - exciting New Research About Both Prevention And Treatment For Alzheimer's Disease And Cognitive decline
Jul 18, 2023
10:35
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Promising new research on drugs Dannanamab and Lecanamab in slowing cognitive decline and reducing Alzheimer's progression. Study shows drug's impact on patients with high tau levels. Research on lean muscle mass reveals 12% reduction in Alzheimer's risk. Potential impact of myokines in preventing Alzheimer's and cognitive decline.
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Quick takeaways
- The drug Dannanamab demonstrates a significant 35% slowing of cognitive decline in early Alzheimer's patients by targeting tau protein levels.
- Individuals with higher lean muscle mass have a 12% lower risk of developing Alzheimer's disease, highlighting the importance of physical fitness and exercise in prevention.
Deep dives
New Drug Shows Promise in Slowing Alzheimer's Disease Progression
A recent clinical trial of a drug called Dannanamab by Eli Lilly demonstrated a 35% slowing of cognitive decline in patients with early Alzheimer's disease. This is the most significant result seen so far in Alzheimer's drug trials, which had previously shown little to no benefit. The drug targets tau protein, implicated in the development of Alzheimer's, and showed the most improvement in patients with low to medium tau levels. However, it is important to note that the drug is not a silver bullet and has shown serious side effects, including deaths.
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