Infinite Loops Jeff Bussgang — The Experimentation Machine (EP.285)
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Oct 9, 2025 In this intriguing conversation, Jeff Bussgang, a venture capitalist and Harvard Business School professor, shares insights from his book, The Experimentation Machine. He discusses how AI is revolutionizing startups by compressing learning time and emphasizes the importance of execution velocity over mere technical advantages. Jeff introduces the concept of 10X founders and joiners, highlighting traits like judgment and a growth mindset. He also warns against being seduced by AI flattery, advocating for rigorous prompts to ensure critical thinking in AI interactions.
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AI Turbocharges Execution Velocity
- AI dramatically compresses the time and cost of learning, enabling far faster execution for founders.
- Execution velocity, not tech moats, becomes the decisive competitive advantage in the AI era.
Use The HUNCH Framework
- Use the HUNCH framework to test product-market fit: Hair-on-fire value props, Usage, NPS, Churn, High unit economics.
- Measure enduring metrics (usage, cohort behavior, LTV/CAC) instead of vanity metrics.
Apply Public-Market Ruthlessness Privately
- Use public-market discipline in private boards: hold founders accountable with data and 'what-if-we-were-public' rigor.
- Combine long-term private strategy with short-term ruthless metrics review.
