How I Built This with Guy Raz Advice Line with Serial Entrepreneur Mark Cuban
46 snips
Jan 29, 2026 
Mark Cuban, serial entrepreneur and investor who built tech companies, owns the Dallas Mavericks, and launched Cost Plus Drugs. He weighs in on breaking into big-box retail, marketing when users and buyers differ, rebooting handcrafted products with premium pricing, tackling seasonality and supply-chain choices, and reshoring drug manufacturing using robotics and transparency.
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Start Over: Bartend And Sell
- Mark Cuban once said he'd bartend at night and sell by day if he had to start over.
- He recommended leaning on strong skills like sales to rebuild a business.
Make Manufacturing Economical First
- Negotiate regulatory and application costs before scaling manufacturing domestically.
- Use modular, robotics-driven production to pivot quickly between drugs and control margins.
Mission Trumps Pure Profit
- Purpose-driven missions sustain long-term entrepreneurial energy and curiosity.
- Mark Cuban finds mission-level goals more motivating than chase for big financial returns.