The Egg Whisperer Show Best Ovarian Stimulation Protocols for IVF with guest Dr. Geoffrey Sher
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Apr 18, 2025 Dr. Geoffrey Sher, a pioneer in IVF and founder of Sher Fertility Solutions, shares his expert insights on individualized IVF protocols. He emphasizes that there’s no 'one size fits all' approach, tailoring treatments based on each woman's age and ovarian reserve. The conversation highlights the critical roles of testosterone and customized hormone protocols in enhancing egg quality. Sher also discusses the balance between risk and success in ovarian stimulation, as well as debunking myths surrounding sperm quality and male fertility treatments.
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Testosterone Balance Crucial for Eggs
- Excess testosterone in the ovary harms egg development and follicle growth, causing premature luteinization.
- Proper testosterone balance is essential for healthy egg maturation and normal meiosis.
Birth Control and Lupron Overlap
- Start IVF cycles using birth control pills overlapped with Lupron to suppress FSH and LH before stimulation.
- This strategy controls cycle timing and improves ovarian responsiveness without suppressing follicle development.
Use GnRH Antagonist for Lower Reserve
- For women with diminished ovarian reserve (AMH < 1.5), switch from Lupron to a GnRH antagonist at cycle start.
- Antagonists prevent Lupron's competitive inhibition on FSH, improving ovarian response.