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TED Health

How do kidney transplants work? | Alexander H. Toledo

Apr 1, 2025
In this engaging discussion, Alexander H. Toledo, an educator in organ transplantation, dives into the history and evolution of kidney transplants, spotlighting the trailblazing 1954 procedure and today's advanced techniques. Leilani Graham, a heart transplant recipient and healthcare consultant, shares her harrowing journey through cardiac arrests and the emotional realities of recovery post-transplant. Together, they tackle the ongoing organ donor shortage and the vital role of compassion in patient care, shedding light on the challenges faced by those awaiting life-saving surgeries.
23:31

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Quick takeaways

  • The evolution of kidney transplantation has advanced from early successful swaps to modern methods that enhance donor-recipient compatibility and reduce rejection risks.
  • Leilani Graham's personal journey underscores the emotional and physical challenges of recovery from organ transplants, highlighting the need for better patient education and support systems.

Deep dives

The Evolution and Importance of Organ Transplants

Organ transplants represent a remarkable medical advancement, significantly changing patients' lives while highlighting a critical shortage of available organs. The podcast outlines the journey from early transplantation attempts, such as Joseph Murray's groundbreaking kidney swap in 1954, to today’s practices that allow better compatibility between donors and recipients. Modern medicine has introduced new drug therapies that reduce the risk of organ rejection, enabling patients to receive kidneys from family members or even strangers through paired exchanges. However, despite these advances, approximately 90,000 patients are on the waiting list for kidneys in the U.S., with 17 people dying each day due to the lack of donors.

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