The Dr. Layne Norton Podcast AMA 05 - Creatine, Plant Protein, Collagen, Fiber, GLP1s and More
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Jun 22, 2026 A rapid-fire Q and A on supplements, protein sources, cholesterol, weight-loss meds and more. Creatine forms, plant versus animal protein counting, and collagen’s limits get tackled. Safety questions on ashwagandha and fiber tips for health are covered. LDL particle debates and practical guidance on GLP-1 medications and preserving muscle during weight loss are discussed.
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Creatine Monohydrate Is The Proven, Cost Effective Choice
- Creatine monohydrate saturates muscle creatine stores fully and matches or exceeds other forms like HCL in effectiveness.
- Head-to-head studies show no performance benefit for creatine HCL while costing 2–4× more, so monohydrate is the evidence-backed choice.
Layne's Personal Take On David Protein Lawsuit
- Layne invested in David Protein and defends its EPG fat technology as non-absorbable, producing ~0.7 kcal/g because the fats pass through undigested.
- He notes an FDA verification and that the lawsuit alleging label failure was dropped, calling the challenge opportunistic.
Plant Protein Counts But Watch Single Source Diets
- All plant proteins contain essential amino acids but some are low in particular ones (e.g., wheat low in lysine), making single-source, low-protein vegan diets the real risk.
- In mixed or high-protein diets (≈1.6 g/kg) plant protein counts fully toward total protein and concern is minimal.