Advantages and Disadvantages of Biomarker-based Endotyping for CC by N. Yehya et al | OPENPediatrics

Listen as Dr. Nadir Yehya, Assistant Professor of Anesthesiology and Critical Care Medicine at the Children's Hospital of Philadelphia and the University of Pennsylvania, discusses the advantages and disadvantages of biomarkers in critical care research. He covers the specifics of how biomarkers influence endotyping, subphenotyping, and enrichment for critical care trials (with a focus on sepsis and ARDS). He also provides an overview of existing literature in adult and pediatric sepsis and ARDS, as well as the strengths and weaknesses of using biomarkers in research. Initial publication: February 21, 2020. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu