Bacteriophages Lurk In Your Bathroom, But Don’t Worry
Nov 20, 2024
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Dr. Erica Hartmann, an associate professor in Civil & Environmental Engineering at Northwestern University, dives into the surprising world of bacteriophages found in our bathrooms. Over 600 different viruses, mostly novel to science, were discovered lurking in showerheads and toothbrushes. She explains how these viruses prey on bacteria and their potential as alternatives to antibiotics amidst growing resistance. The conversation also touches on the historical efforts in bacteriophage research and the need for modern techniques to unlock their medical possibilities.
The surprising discovery of over 600 bacteriophages lurking in bathrooms highlights the rich microbial biodiversity present in everyday environments.
As antibiotic resistance increases, renewed interest in bacteriophage research may lead to innovative therapeutic strategies against resistant bacterial infections.
Deep dives
Bathroom Biodiversity and Bacteriophages
Research has revealed a surprising diversity of viruses, specifically bacteriophages, lurking in household bathrooms. These viruses prey on bacteria and pose no threat to human health, as they do not infect people. Samples obtained from toothbrushes and showerheads demonstrated that each location hosts a unique mix of viruses, showcasing significant variability between different samples. This biodiversity suggests that studying these environments may provide insights into the broader microbial ecosystems present in the built environments where people spend most of their time.
Sources of Bacteria and Their Viruses
The bacteria and bacteriophages found in bathrooms originate from various sources, with the water supply being a significant contributor. While toothbrushes mainly accumulate bacteria from the mouth, they can also collect microbes from the surrounding air and water. Conversely, showerheads primarily acquire their microbial populations through the plumbing system, reflecting differences in water treatment methods. Understanding these pathways can help researchers address microbial exposures in domestic environments more effectively.
The Future of Phage Research
There is a renewed interest in bacteriophage research as traditional antibiotics become less effective against resistant bacteria. The science community is actively exploring the potential for these phages to serve as therapeutic agents, particularly for designing broad-spectrum phages that can target multiple bacterial strains. Advancements in molecular biology techniques, including DNA sequencing, allow for a more nuanced understanding of phage behavior and their interactions with hosts. By cataloging viral diversity, researchers aim to develop novel therapeutic strategies and tools to combat infections and improve public health.
It sounds like something from an advertisement for bathroom cleaner: Researchers found over 600 different viruses, most of which are new to science, in samples taken from showerheads and toothbrushes. The viruses, however, are unlikely to affect humans. They are bacteriophages, a type of virus that preys on bacteria. The expedition into bathroom biodiversity was recently published in the journal Frontiers in Microbiomes.
Around a hundred years ago in the former Soviet Union, there were major efforts to develop bacteriophages for medical use. The approach really didn’t catch on in Western countries, overshadowed there by the rise of conventional antibiotics like penicillin. But with some diseases developing resistance to those conventional antibiotics, there’s been increased interest in phages as part of an antibacterial toolkit.
Dr. Erica Hartmann, an associate professor in the department of Civil & Environmental Engineering at Northwestern University, joins Ira to talk about what researchers found when they took a close look at a collection of bathroom samples, and how phage research has advanced in recent years.
Transcript for this segment will be available after the show airs on sciencefriday.com.