The Dr. Hyman Show Exclusive Dr. Hyman+ Ask a Doctor: Gut Health and Alzheimer’s, Genetic Risk of Disease, And More
Jan 30, 2024
Discover intriguing insights into the link between gut health and Alzheimer’s disease, highlighting how inflammation impacts cognitive decline. Learn about the genetic marker lipoprotein(a) and its connection to vascular disease risks. Explore the double APOE4 gene variant's effect on dementia, emphasizing that having it doesn't guarantee disease onset. Dietary strategies, including the MIND diet, are discussed to help manage dementia risk. This engaging conversation encourages awareness of lifestyle choices that can enhance overall health.
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Managing Lipoprotein(a)
- Test lipoprotein(a) once, as levels remain relatively stable.
- If it's high, consider niacin, CoQ10, or PCSK9 inhibitors, but understand lifestyle changes have limited impact.
Gut Health and Alzheimer's
- Gut health and Alzheimer's are linked, as gut imbalances can cause inflammation, a dementia trigger.
- Methane-dominant SIBO, marked by constipation and bloating, can be chronic but isn't always.
APOE4 and Diet
- For those with APOE4 gene variant, follow the MIND diet, a Mediterranean diet variation.
- Prioritize omega-3 fats from fish, flax, and walnuts and aim for 8-12% omega-3s in red blood cell membranes.