Bryan Johnson Podcast Ketamine & Cocaine: Ranking Drugs for Longevity (Part 1)
Sep 4, 2025
Can certain drugs help you live longer? The discussion tackles ketamine and cocaine, revealing surprising insights about their effects. Hear about the therapeutic benefits of ketamine for mental health and its potential to reshape the brain. The hosts reflect on shifting views of psychedelics and navigate the social norms surrounding drug use. They also examine historical contexts and safety concerns, such as the risks of fentanyl contamination. It's a mix of humor and serious reflection on the complex landscape of substance use.
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Cocaine Dramatically Reduces Lifespan
- Heavy cocaine use increases mortality dramatically, similar to or worse than chronic smoking.
- Studies show heavy users face a 4–8x death risk and about 10.8 years of life lost per daily use estimate.
Cocaine Was Once Kept In Hospital Pyxis
- Dr. Mallin recounted hospitals stocking small amounts of cocaine to treat severe nosebleeds.
- The drug was tightly controlled in the Pyxis and required multiple people to access it.
Carry Naloxone And Fentanyl Test Strips
- If you use street drugs, carry naloxone and keep fentanyl test strips on hand to reduce overdose risk.
- Buy nasal naloxone and test strips online and keep them accessible for friends and travel.