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Drug Addiction, Cocaine, Nicotine, Caffeine, Amphetamines, Opioids, THC & Neuroscience | Christian Luscher | 40

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Oct 14, 2021

01:08:02

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INSIGHT

Addiction Prevalence

Roughly 20% of people develop addiction when exposed to drugs like cocaine.
This is similar in mice, suggesting addiction isn't solely genetic.

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INSIGHT

Addiction Heritability

The heritability of addiction is complex and not solely determined by genetics.
Epigenetic differences and life experiences play a significant role.

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INSIGHT

Seeking vs. Taking

Drug addiction research distinguishes between drug-seeking and drug-taking.
Addicts prioritize the seeking process, although both behaviors share overlapping brain circuits.

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Drug Addiction in Lab Mice and Humans?

05:29 • 2min

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Drug Dependence and Compulsion in Animals

07:26 • 2min

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Compulsive Drug Behavior

09:29 • 3min

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The Difference Between Drug Seeking and Drug Taking Behavior

12:00 • 2min

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Dopemin and Addiction - How Do They Work?

13:46 • 3min

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Drugediction - Which Parts of the Brain Are Responsible for Habitual Behavior?

16:50 • 2min

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Dopemin Signalling in Drug Addiction

Is the Orbital Frontal Cortex a Code for the Decision That an Individual Takes?

25:15 • 2min

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What Happens if You Remove Cocaine or Cocaine?

27:20 • 2min

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Is Cocaine Dependent on a Drug?

29:16 • 2min

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The Difference Between Psychodelics and Addictive Drugs

30:50 • 4min

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Dopemin - How Do Drugs Work?

34:45 • 2min

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Are Prescription Stimants Addictive?

37:09 • 2min

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What Is the Physiological Rule of the Norons in the Dopamin System?

39:37 • 4min

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Is There a Difference Between Addiction and Dependency?

43:56 • 5min

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The Role of Serotonan in the Addiction Process?

48:31 • 4min

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Dopamine and Serotonin Are the Key Defining Factors in Addiction

52:31 • 2min

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Are You Taking Cocain With Cocaine?

Drug Addiction and Food Addiction - What's on the Horizon?

58:54 • 2min

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Is There a Predictive Effect of Cocaine on Addiction in Lab Animals?

01:00:43 • 5min

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Deep Brain Stimulation Is Used to Treat Parkinson's Disease

01:06:13 • 2min

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Send us a text

Christian Luscher, MD, PhD is a neuroscientist and neurologist who runs a research lab at the University of Geneva in Switzerland. Dr. Lusher's lab studies the mechanisms that underlie drug reinforcement and addiction in the brain and he is an expert in the neuroscience of drug addiction.

Christian talks to Nick about: what is addiction is and what some key parts of the brain and neurotransmitter systems are involved in drug addiction; differences in the addictive potential of different types of drugs, ranging from stimulants (e.g. cocaine, nicotine, caffeine) to cannabinoids (e.g. THC), opioids, and psychedelics; the difference between addiction vs. dependency, habitual vs. goal-directed behavior; latest research on how dopamine & serotonin systems in the brain are both involved in drug-seeking behavior.

*Not medical advice.

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