45. Your Brain Thinks Anxiety = Safety—Here’s How to Rewire It with Scott Sherr

Why does it feel like no matter how well we eat, exercise, or manage stress, something still isn’t quite right?

In this episode, I sit down with Dr. Scott Sherr, an expert in integrative medicine and hyperbaric oxygen therapy, to explore the missing links in modern health: oxygen, mitochondria, and nervous system regulation.

We dive into the science of energy production, the impact of chronic stress on the body, and why so many of us are operating in survival mode without even realizing it. Dr. Sherr also breaks down cutting-edge therapies like hyperbaric oxygen, methylene blue, and low-dose nicotine—how they work, who they’re for, and why they’re often misunderstood.

Whether you're struggling with brain fog, fatigue, or burnout, or simply want to optimize your health on a deeper level, this episode is packed with insights that could change the way you think about healing and longevity.

Dr. Scott Sherr is a board-certified internal medicine physician specializing in integrative health, hyperbaric oxygen therapy, and cutting-edge longevity treatments. He is the founder of OneBase Health, a company focused on optimizing health through advanced technologies, and a leader in the field of Health Optimization Medicine & Practice (HOMe/HOPe). His approach merges Western science with holistic strategies, helping people restore energy, resilience, and overall well-being.

We Also Discuss:

(00:00) The truth about health & wellness—why doing "everything right" isn’t always enough

(14:06) How chronic stress rewires your nervous system (and what to do about it)

(18:23) The missing link in healing: resilience, energy, and nervous system balance

(29:40) The science behind hyperbaric oxygen therapy—how it fuels deep healing

(36:39) Can oxygen slow aging? The surprising link between hyperbaric therapy & longevity

(44:26) Why when you use hyperbaric therapy matters more than how you use it

(54:31) Beyond traditional medicine: optimizing health through biomarker testing

(01:16:18) The mitochondria reset—why fixing your energy production changes everything

Thank You to Our Sponsors:

Fatty15: Fatty15 is on a mission to optimize your C15:0 levels and help you live healthier, longer. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MONA   and using code MONA at checkout.

Cymbiotika: Use the code Monasharma for 20% at https://cymbiotika.com/. 

Rooted Academy: Ready to reclaim your health and transform your well-being? Join Rooted Academy by Mona Sharma, a science-backed, community-driven wellness platform designed to help you heal from within. Enroll today and start your journey to balance, vitality, and lasting transformation. https://www.monasharma.com/rooted

Learn more about Mona Sharma:

Download Your FREE Guide - 12 Wellness Tips to Unlock Your Best Health Now: Ready to reclaim your vitality? Download Mona’s 12 Wellness Tips and take actionable steps to transform your health, energy, and mindset. Get started now at https://monasharma.com/12tips.

Visit Mona's website: https://monasharma.com – Unlock powerful tools and wisdom rooted in wellness to elevate your health, energy, and clarity. Mona blends ancient healing practices with modern science to help you achieve lasting transformation.

Follow Mona on Instagram: Stay connected with Mona for daily inspiration, holistic health tips, and personal growth. Join the conversation on Instagram at https://instagram.com/monasharma.

Learn more about Dr. Scott Sherr

Instagram: @drscottsherr

Website: www.onebasehealth.com