Recap: What is inflammation and how can I control it | Prof. Philip Calder
Jan 21, 2025
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Prof. Philip Calder, an inflammation expert and Head of the School of Human Development and Health at the University of Southampton, delves into the complexities of inflammation. He discusses its role in the immune response and its connection to chronic diseases like arthritis and diabetes. Calder emphasizes the importance of omega-3 fatty acids from oily fish for managing inflammation and improving health. Additionally, he highlights the nutritional differences between wild and farmed salmon, urging smarter food choices for better health outcomes.
Inflammation serves as both a protective immune response and a potential threat when poorly regulated, affecting overall health significantly.
Dietary choices, particularly the intake of anti-inflammatory foods like omega-3 fatty acids and vitamin C, can effectively manage inflammation levels.
Deep dives
Understanding Inflammation and Immunity
Inflammation is a crucial part of the body's immune response, acting as the first line of defense against harmful agents such as bacteria and viruses. It is often misunderstood, with many people conflating it with immunity itself. While inflammation can be beneficial and helps to heal injuries, it can also become harmful if it is not properly regulated or occurs inappropriately. Conditions like arthritis, multiple sclerosis, and type 1 diabetes showcase the consequences of unchecked inflammation, highlighting the need for better understanding and management of this biological response.
The Impact of Low-Grade Inflammation
Many individuals living modern lifestyles experience elevated levels of inflammation, particularly low-grade inflammation, which is linked to various chronic diseases. Unlike high-grade inflammation, which is easily identifiable through symptoms and blood markers like C-reactive protein (CRP), low-grade inflammation can persist without obvious symptoms. This type of inflammation has been associated with conditions such as heart disease, obesity, type 2 diabetes, and even dementia. Understanding how lifestyle factors contribute to this persistent inflammation can aid in preventive health measures and disease management.
Dietary Strategies to Combat Inflammation
Incorporating specific dietary elements can play a significant role in managing inflammation levels within the body. Nutritionists recommend a shift towards anti-inflammatory foods, such as omega-3 fatty acids found in oily fish, vitamin C-rich fruits, nuts, and other plant-based sources. Studies indicate that a diet rich in these nutrients can help not only mitigate ongoing inflammation but also assist in its resolution. Additionally, while some factory-farmed fish may offer lower levels of beneficial omega-3s, they still remain a viable source, demonstrating the importance of maintaining a balanced diet for overall health.
We hear this word a lot from guests on the ZOE podcast. It’s always coming up when we ask questions about health conditions like Alzheimer's, cancer or heart disease.
It’s clearly very important, however many of us still don’t fully understand what inflammation really is.
Professor Phillip Calder is here to break down inflammation and share tips on what we should eat to keep it in check. Philip is Head of the School of Human Development and Health in the Faculty of Medicine at the University of Southampton.
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