Mayo Clinic Talks
Lab Medicine Edition | CBC: Platelets (Thrombocytosis, Thrombocytopenia)
May 9, 2024
Dr. Ronald S. Go discusses abnormal platelet test results and their implications on patient care. Topics include the differentiation between reactive and primary causes of elevated platelet counts, diagnostic considerations post-transfusion, detecting platelet clumping in blood samples, differentiating serious platelet disorders, and advancements in platelet apheresis.
30:22
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Quick takeaways
- Platelet counts above 350 raise concerns, with levels over 600 considered significant, and counts exceeding 1,000 signal immediate attention.
- A platelet count below 100 warrants closer examination, as isolated thrombocytopenia may stem from production, destruction, or hypersplenism issues.
Deep dives
Understanding Platelet Counts in CBC
Elevated platelet counts above 350, with readings outside the reference range, may cause concern, especially if reaching 600 or higher. Concern heightens significantly if counts surpass 1,000. Reactive causes are common culprits, with primary causes being less frequent. Inflammatory conditions, infections, or cancer-related factors often contribute to reactive elevation.
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