The Matt Walker Podcast cover image

The Matt Walker Podcast

#02: Sleep Pressure

Aug 16, 2021
08:44

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Quick takeaways

  • Sleep pressure is caused by the build-up of adenosine throughout the day, signaling to the brain that it's time to sleep.
  • Caffeine can block the sleepiness signal by competing with adenosine for brain receptors.

Deep dives

Sleep pressure: Build up of adenosine and its effects

Sleep pressure is caused by the build-up of a chemical called adenosine in the brain throughout the day. As you stay awake, the levels of adenosine increase, signaling to your brain that it's time to sleep. High levels of adenosine in the evening turn down wake-promoting areas of the brain and enhance sleep-inducing regions, leading to a strong desire to sleep. This sleepiness can be countered by consuming caffeine, which competes with adenosine for brain receptors, effectively blocking the sleepiness signal.

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