

The Matt Walker Podcast
Dr. Matt Walker
The Matt Walker Podcast is all about sleep, the brain, and the body. Matt is a Professor of Neuroscience at the University of California, Berkeley. He is the author of the book, Why We Sleep and has given a few TED talks. Matt is an awkward British nerd who adores science and the communication of science to the public.
Episodes
Mentioned books

50 snips
Oct 20, 2025 • 20min
#111 - The Price of Sleep
Sleep is reimagined as a vital economic asset rather than just a need. Sleep deprivation costs the U.S. economy up to $411 billion annually due to decreased productivity and increased healthcare costs. Extended wakefulness can impair cognitive function similarly to intoxication, raising safety concerns. By investing in sleep programs, businesses can see significant returns, while individuals enjoy better financial outcomes linked to adequate rest. Ultimately, prioritizing sleep is framed as an investment yielding benefits for both personal well-being and economic prosperity.

74 snips
Oct 13, 2025 • 1h 2min
#110 - The Science Behind Wearable Sleep Monitoring
Dive into the fascinating world of sleep tracking technology! Discover how motion and optical sensors work together and the critical distinctions between absolute and relative accuracy. Explore peer-reviewed insights on devices like the Oura Ring, Apple Watch, and the innovative Happy Ring. Uncover the pitfalls of tracking, including orthosomnia and demographic biases, while understanding why consistency in using these tools is more important than perfect accuracy. Learn to harness sleep trackers for long-term health optimization.

89 snips
Oct 6, 2025 • 52min
#109 - How to Get More REM Sleep
The podcast dives deep into the fascinating world of REM sleep, highlighting its key role in emotional regulation and creativity. Discover how neurotransmitters like acetylcholine enhance REM and learn about medications that can boost this vital sleep stage. Explore practical strategies like adjusting light exposure, eating complex carbohydrates, and practicing stress management to support REM sleep. Innovative technologies such as electrical brain stimulation are also discussed, offering a glimpse into the future of sleep enhancement.

Sep 29, 2025 • 30min
Cozy Cabin Retreat: A Sleep Story Read by Matt Walker
Drift into a world of tranquility as you're guided through a cozy cabin retreat. Experience calming visualization techniques that transport you to a serene haven, embracing soft lights and soothing scents. Engage in a soothing tea ritual, followed by a peaceful gazing at the moonlit sky. Let go of your worries by visualizing them as leaves floating away on a gentle river. Ease into relaxation with rhythmic breathing and a weighted blanket, leading to deep, restorative sleep. Awaken refreshed, ready to embrace tomorrow's joys.

33 snips
Sep 22, 2025 • 25min
#108 Implanting False Memories Into Your Brain
Discover the surprising ways our memories can be distorted and manipulated. From experiments showing how language can alter our recollections to groundbreaking research on implanted false memories, the fluid nature of memory is explored. Learn about therapies that can help with nightmares and PTSD by modifying memories. The implications for identity, truth, and forgiveness are profound, highlighting that these concepts are not fixed but rather dynamic constructs. Memory might just be more of a creative process than a factual archive!

64 snips
Sep 15, 2025 • 1h 29min
#107 - Medicine 3.0 with Dr. Avinish Reddy
Dr. Avinish Reddy, Founder and CEO of Elevated Medical, shares insights on longevity and healthcare innovation. He stresses the crucial link between physical, mental, and social well-being, revealing that social isolation can heighten mortality risk like smoking. Dr. Reddy advocates for advanced diagnostics to assess cardiovascular health and underscores the importance of early lifestyle interventions. He highlights the value of personalized care, emphasizing daily movement, nutrition, and strength training for optimal health as we age.

43 snips
Sep 8, 2025 • 45min
Ask Me Anything Part 22: Latitude, Pain Gating, Temperature & Shift Work
Discover how extreme latitudes affect sleep patterns, with practical tips for managing light exposure. Learn about the importance of aligning sleep with one's chronotype and debunk myths like the 'sleep before midnight' concept. Delve into the brain's pain suppression mechanisms during sleep and the role of significant auditory stimuli. Gain insights into temperature regulation for better sleep quality, especially for shift workers. This lively discussion blends science and personal experiences to illuminate the complexities of sleep.

91 snips
Sep 1, 2025 • 30min
#106 - Can A Sleeping Pill Help Fight Alzheimer’s?
Matt dives into the fascinating connection between sleep and Alzheimer’s, highlighting how the brain’s glymphatic system cleanses harmful proteins during deep sleep. He uncovers the dangers of chronic sleep deprivation, which can exacerbate cognitive decline. Exciting research on new sleep medications, particularly orexin antagonists, suggests they may enhance this cleaning process and offer neuroprotection. Findings indicate these drugs could potentially improve Alzheimer’s biomarkers. Prioritizing high-quality sleep emerges as a vital strategy for long-term brain health.

73 snips
Aug 25, 2025 • 1h 1min
Ask Me Anything Part 21: Sleep Debt, Snooze Button, Naps & Sleep Myths
Join two experts as they tackle the snooze button's negative impact on sleep quality and share strategies for waking up more effectively. Discover the truth behind sleep debt, the effects of eating salt at night, and the myths surrounding sleep aids like grounding sheets. They also explore how different sleep stages can influence mood and examine sleep fragmentation and its health effects. Finally, learn about innovative research linking mitochondrial stress to sleep patterns, revealing new insights into the science of sleep.

75 snips
Aug 18, 2025 • 21min
#105 - Delta Sleep Inducing Peptides
Discover the intriguing rise and fall of Delta Sleep-Inducing Peptide, once thought to be the miracle cure for insomnia. In the 1970s, researchers celebrated its ability to induce deep sleep in animals, stirring excitement across the scientific community. However, as cautionary tales unfolded, the dream of a simple solution to sleep issues faded. Hold onto your pillow as the complex nature of sleep regulation and the problems of scientific overconfidence are unveiled, reminding us there's no one-size-fits-all remedy for restful slumber.