Instant Genius

The science behind Agatha Christie’s poisons

Jun 12, 2025
Kathryn Harkup, a chemist and author of 'V is for Venom: Agatha Christie’s Chemicals of Death,' dives into the fascinating world of poisons in Agatha Christie's novels. She reveals Christie's remarkable grasp of chemistry, showcasing a variety of deadly substances that enrich her plots. Listeners will learn about the dual nature of compounds like phosphorus and the chilling effects of drugs like opium. The discussion offers a captivating blend of science and storytelling, making it both enlightening and a bit macabre!
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INSIGHT

Diverse Mechanisms of Poisons

  • Poisons work in diverse ways and produce a wide range of symptoms. - There is no single predictable outcome when someone is poisoned.
ANECDOTE

Phosphorus: A Favorite Poison

  • Kathryn Harkup's favorite poison is phosphorus due to her chemistry background. - Agatha Christie used phosphorus in her novel "Dumb Witness" showcasing its gruesome effects.
INSIGHT

Deadly Liver Damage by Phosphorus

  • White phosphorus kills mainly by destroying the liver function. - The only antidote is a liver transplant, making it highly lethal.
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