

Menopause Brain Fog Is Real: 7 Science-Backed Ways To Clear It | Dr. Jolene Brighten
Menopause brain fog is the short-term difficulty with focus, word-finding, and memory that can show up in perimenopause and early postmenopause. It’s driven by estradiol fluctuations, declining progesterone/allopregnanolone (ALLO), and sleep fragmentation from hot flashes. The good news? It’s usually reversible with symptom treatment and daily habit shifts. Listen to this episode for the full brain-chemistry tour and a practical plan to feel clearer, calmer, and more you.
Chapters
00:00:00 Menopause Brain Fog: Who This Episode Helps
00:03:00 Perimenopause Timeline: 7–10 Years
00:06:00 Hormones that affect sleep
00:07:00 Women’s Testosterone: Drive, Initiation, Libido
00:09:00 HRT “Critical Window” + Insulin Resistance
00:11:00 Menopause Brain Fog Explained: “Software Update” Model
00:13:00 Endocrine Age vs Chronological Age: Why It Matters
00:14:00 My Story: Mood Crash & Lost Mental Edge
00:19:00 Menopause Brain Fog vs ADHD: Executive Function Clues
00:26:00 Hormone Stage Drives Brain
00:28:00 Estrogen, Dopamine, GABA: Memory & Focus Pathways
00:33:00 Signs to Look Out For
00:39:00 Hot Flashes Fragment Deep & REM Sleep (Here’s Why)
00:46:00 Will Brain Fog Go Away? SWAN Data & Adaptation
00:48:00 Medical Conditions That Cause Brain Fog
00:50:00 Focus Tools
00:55:00 Sleep Protocol: Fix Wake Time, Morning Light, Cool Room
00:57:00 Exercise & Brain Health
00:58:00 Saffron (Affron®): Mood, Sleep, Libido Support
01:01:00 Citicoline (Cognizin®): Attention & Mental Energy
01:04:00 Bacopa (Bacognize®): Memory & Calm Focus
01:08:00 Magnesium & Brain Health: Sleep, Migraines, Aging
01:18:00 Nervous System Downshift
01:22:00 CBT-I/ACT for Midlife Brain Fog & Rumination
01:23:00 Surgical Menopause & Dementia Risk
01:31:00 Key Takeaways
🎧For the entire show notes + links mentioned in the episode, please visit: https://drbrighten.com/podcasts/menopause-brain-fog/
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