The Dr. Brighten Show

Dr. Jolene Brighten
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Dec 23, 2025 • 22min

Estrogen Cream for the Face: What the Science Says About Anti-Aging, Collagen, and Hormones

Is estrogen cream for the face really the new holy grail of anti-aging—or is it another skincare trend overselling its promise? In this episode of The Dr. Brighten Show, Dr. Jolene Brighten breaks down the biology behind estrogen and skin aging, why women’s skin often changes rapidly after 35, and what clinical studies actually show about using topical estrogen on the face. This isn’t about chasing youth—it’s about understanding collagen loss, inflammation, and how hormonal shifts during perimenopause and menopause directly affect the skin. What You’ll Learn in This Episode In this episode, you’ll learn how estrogen interacts with the skin at a cellular level, why traditional skincare often stops working in midlife, and how clinicians are using estrogen cream for the face—specifically estriol and estradiol—in a thoughtful, medically supervised way. Dr. Brighten explains who may benefit, how these creams are typically used, what results are realistic, and which healthcare providers are qualified to prescribe them, all through a women’s-health-first, evidence-based lens. This Episode Is Brought to You By Dr. Brighten Essentials Radiant Mind—a science-backed formula created to support women’s brain health through every stage of life. If you’ve ever felt the brain fog of perimenopause or noticed how ADHD can amplify challenges with focus, memory, mood, or sleep, you’re not alone. Radiant Mind combines clinically studied saffron extract, Bacognize® Bacopa, Cognizin® Citicoline, and zinc to help nourish your brain chemistry and support clarity, calm, and resilience.  Shop now https://drbrighten.com/radiant/ OneSkin  Founded by an all-woman team of PhD-level scientists, OneSkin is revolutionizing aging with the OS-01™ peptide, the first ingredient proven to reverse skin’s biological age by targeting cellular senescence. The result? Skin that looks, feels, and acts younger. It’s never too early — or too late — to invest in your skin health. Shop now https://oneskin.pxf.io/c/1950532/2885132/31050 LUMEBOX Ready to take your skincare results to the next level—right from home? 💡 LUME Box delivers professional-grade LED light therapy in a sleek, easy-to-use device that targets fine lines, pigmentation, and dullness at the cellular level. Just minutes a day can help boost collagen, calm inflammation, and reveal that lit-from-within glow. It’s the same science trusted in top dermatology clinics, now in your hands. Shop now → https://drbrighten.com/lumebox use code drbrighten for our exclusive community discount on your purchase. 👩🏻‍⚕️Follow Dr. Jolene Brighten: 💻 Website:⁠⁠ https://www.drbrighten.com⁠⁠ 📸  Instagram:⁠⁠⁠ ⁠https://www.instagram.com/drjolenebrighten⁠ 🎥 TikTok: ⁠⁠https://www.tiktok.com/@drjolenebrighten⁠⁠ 🧵Threads: ⁠⁠https://www.threads.net/@drjolenebrighten⁠⁠ 🌟 Grab my free hormone friendly recipes here! ⁠⁠https://drbrighten.com/hormonekit/⁠⁠ 🎧 Subscribe to the Podcast: Apple: ⁠⁠https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161⁠⁠ Spotify: ⁠⁠https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417⁠⁠ YouTube:⁠ ⁠https://www.youtube.com/@drjolenebrighten⁠⁠⁠ 👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨  Learn more about your ad choices. Visit megaphone.fm/adchoices
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Dec 18, 2025 • 35min

Doctor Reacts to Lili Reinhart and Breaks the Endometriosis Diagnosis Myth | Dr. Jolene Brighten

Endometriosis shouldn’t require fame, influence, or extraordinary persistence to be taken seriously—yet that’s exactly what Lili Reinhart’s viral post reveals. In her deeply vulnerable message, she shared years of worsening symptoms, medical dismissal, and confusion that ultimately led her to discover she had both endometriosis and adenomyosis. Her experience mirrors the journey of millions of people who have been repeatedly told their pain is normal, exaggerated, or unrelated to their reproductive health. In this powerful episode of The Dr. Brighten Show, Dr. Jolene Brighten reacts to Lili’s post and uses it as a launch point to expose the endometriosis diagnosis myth, highlight the systemic failures that keep patients undiagnosed for years, and provide a clear, practical path for listeners who suspect endo but haven’t been taken seriously. Drawing from her own 29-year delay to diagnosis, her clinical expertise, and the lived experiences of her community, Dr. Brighten breaks down the biggest misconceptions, the biases baked into diagnostic processes, and the tools that actually help patients get answers. You’ll learn why “normal” imaging is often meaningless, how endometriosis can hide from inexperienced radiologists, and why patients who tell doctors they want to conceive get diagnosed faster—even when their symptoms are the same. You’ll also learn how pelvic floor dysfunction, bladder symptoms, digestive issues, fatigue, and systemic inflammation all intersect with endometriosis and what this means for your care. This Episode Is Brought to You By Dr. Brighten Essentials Radiant Mind—a science-backed formula created to support women’s brain health through every stage of life. If you’ve ever felt the brain fog of perimenopause or noticed how ADHD can amplify challenges with focus, memory, mood, or sleep, you’re not alone. Radiant Mind combines clinically studied saffron extract, Bacognize® Bacopa, Cognizin® Citicoline, and zinc to help nourish your brain chemistry and support clarity, calm, and resilience.  Shop now https://drbrighten.com/radiant/ Sunlighten Saunas Want a gentle, science-forward way to sweat, recover, and unwind?  At Sunlighten, infrared saunas deliver soothing heat that supports relaxation, muscle recovery, and deep, comfortable sweating—without the stifling temps of traditional saunas. With low-EMF tech and options for near, mid, and far infrared, you get a calm, restorative session tailored to your goals. Exclusive for podcast listeners: use the code DRBRIGHTEN to save up to $1,400 on your sauna Shop now https://get.sunlighten.com/drbrighten LUMEBOX Ready to take your skincare results to the next level—right from home? 💡 LUME Box delivers professional-grade LED light therapy in a sleek, easy-to-use device that targets fine lines, pigmentation, and dullness at the cellular level. Just minutes a day can help boost collagen, calm inflammation, and reveal that lit-from-within glow. It’s the same science trusted in top dermatology clinics, now in your hands. Shop now → https://drbrighten.com/lumebox use code drbrighten for our exclusive community discount on your purchase. 👩🏻‍⚕️Follow Dr. Jolene Brighten: 💻 Website:⁠ https://www.drbrighten.com⁠ 📸  Instagram:⁠ https://www.instagram.com/drjolenebrighten 🎥 TikTok: ⁠https://www.tiktok.com/@drjolenebrighten⁠ 🧵Threads: ⁠https://www.threads.net/@drjolenebrighten⁠ 🌟 Grab my free hormone friendly recipes here! ⁠https://drbrighten.com/hormonekit/⁠ 🎧 Subscribe to the Podcast: Apple: ⁠https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161⁠ Spotify: ⁠https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417⁠ YouTube:⁠ https://www.youtube.com/@drjolenebrighten⁠⁠ 👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨  Learn more about your ad choices. Visit megaphone.fm/adchoices
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8 snips
Dec 16, 2025 • 1h 1min

How to Lower Cortisol & RESET Your Nervous System in 90 Seconds | Rosie Acosta

Rosie Acosta, a mindfulness teacher and bestselling author, joins to explore stress reduction and nervous system regulation. She shares a 90-second breathing technique to lower cortisol and activate the vagus nerve. Rosie discusses the misconceptions around mindfulness and productivity, emphasizing that even short practices can reshape the brain. Insights include turning chores into mindful rituals and the benefits of reducing social media usage. Her morning routine and quick mindfulness tools offer practical ways to cultivate calm and presence daily.
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Dec 11, 2025 • 1h 15min

The Hidden Hormone Disorder: How Isolation Disrupts Cortisol, Sleep & Emotional Stability | Shawn Stevenson

Loneliness isn’t just an emotional experience—it’s a biological event that behaves like a hidden hormone disorder. In this episode, Shawn Stevenson joins Dr. Brighten to expose how the effects of social isolation ripple across your cortisol levels, immune system, emotional stability, and even your genes. You’ll hear how technology, toxic relationships, fractured community networks, and modern family dynamics are driving a quiet but powerful shift in women’s health and longevity. What follows is one of the most illuminating, compassionate, and actionable conversations you’ll ever hear about connection, stress, and the biology of belonging. This Episode Is Brought to You By Dr. Brighten Essentials Radiant Mind—a science-backed formula created to support women’s brain health through every stage of life. If you’ve ever felt the brain fog of perimenopause or noticed how ADHD can amplify challenges with focus, memory, mood, or sleep, you’re not alone. Radiant Mind combines clinically studied saffron extract, Bacognize® Bacopa, Cognizin® Citicoline, and zinc to help nourish your brain chemistry and support clarity, calm, and resilience. And for a limited time, when you order Radiant Mind, you’ll also receive a free bottle of our best-selling Magnesium Plus—the perfect partner for restorative sleep and steady mood. Learn more at http://drbrighten.com/radiant. Sunlighten Saunas Want a gentle, science-forward way to sweat, recover, and unwind?  At Sunlighten, infrared saunas deliver soothing heat that supports relaxation, muscle recovery, and deep, comfortable sweating—without the stifling temps of traditional saunas. With low-EMF tech and options for near, mid, and far infrared, you get a calm, restorative session tailored to your goals. Exclusive for podcast listeners: use the code DRBRIGHTEN to save up to $1,400 on your sauna Shop now https://get.sunlighten.com/drbrighten OneSkin  Founded by an all-woman team of PhD-level scientists, OneSkin is revolutionizing aging with the OS-01™ peptide, the first ingredient proven to reverse skin’s biological age by targeting cellular senescence. The result? Skin that looks, feels, and acts younger. It’s never too early — or too late — to invest in your skin health. Shop now https://oneskin.pxf.io/c/1950532/2885132/31050 🔥 Follow Shawn Stevenson: 📸  Instagram: https://www.instagram.com/shawnmodel/ 👥 Facebook: https://www.facebook.com/TheModelHealthShow ⭕ YouTube: https://www.youtube.com/channel/UCtFV6nJ5zZ0__SXBkikfLlg 👩🏻‍⚕️Follow Dr. Jolene Brighten: 💻 Website: https://www.drbrighten.com 📸  Instagram: https://www.instagram.com/drjolenebrighten 🎥 TikTok: https://www.tiktok.com/@drjolenebrighten 🧵Threads: https://www.threads.net/@drjolenebrighten 🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/ 🎧 Subscribe to the Podcast:  Apple: https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161 Spotify: https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417 YouTube: https://www.youtube.com/@drjolenebrighten 👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices
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6 snips
Dec 9, 2025 • 25min

How to Reduce Stress Hormones Naturally (4-Step Plan)

Feeling overwhelmed and fatigued? Discover a simple four-step plan to naturally reduce stress hormones and regain balance. Learn how stabilizing blood sugar can ease cortisol spikes and the importance of protein and hydration. Get practical tips for navigating holiday gatherings with snacks that won't derail your health. Find out about effective winding-down techniques for better sleep and micro nervous-system regulation strategies. Plus, hear how to prepare a December 'Nervous System' first-aid box to thrive during the holiday season.
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Dec 4, 2025 • 30min

5 Science-Backed Steps to Stop Female Hair Loss and Regrow Your Hair

If you've noticed more hair in your brush, shedding in the shower, or a widening part line, you're in the right place. This episode breaks down the real reasons women lose hair and exactly what you can do about it. Because I promised in the episode that everything would be clearly divided into categories in the show notes, this page includes a step-by-step, science-backed protocol, organized by mechanism so you can easily follow and implement the plan. This Episode Is Brought to You By Dr. Brighten Essentials Radiant Mind—a science-backed formula created to support women’s brain health through every stage of life. If you’ve ever felt the brain fog of perimenopause or noticed how ADHD can amplify challenges with focus, memory, mood, or sleep, you’re not alone. Radiant Mind combines clinically studied saffron extract, Bacognize® Bacopa, Cognizin® Citicoline, and zinc to help nourish your brain chemistry and support clarity, calm, and resilience.  Shop now https://drbrighten.com/radiant/ OneSkin  Founded by an all-woman team of PhD-level scientists, OneSkin is revolutionizing aging with the OS-01™ peptide, the first ingredient proven to reverse skin’s biological age by targeting cellular senescence. The result? Skin that looks, feels, and acts younger. It’s never too early — or too late — to invest in your skin health. Shop now https://oneskin.pxf.io/c/1950532/2885132/31050 👩🏻‍⚕️Follow Dr. Jolene Brighten: 💻 Website: https://www.drbrighten.com 📸  Instagram: https://www.instagram.com/drjolenebrighten 🎥 TikTok: https://www.tiktok.com/@drjolenebrighten 🧵Threads: https://www.threads.net/@drjolenebrighten 🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/ 🎧 Subscribe to the Podcast:  Apple: https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161 Spotify: https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417 YouTube: https://www.youtube.com/@drjolenebrighten 👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Dec 3, 2025 • 1h 52min

Pain During Sex, Causes, Symptoms & When to See a Doctor | Dr. Ana Sierra

In this powerful and deeply validating conversation, we unpack what pain is actually telling you, how doctors should evaluate it, why so many women are misdiagnosed, and the anatomical truths every woman deserves to know about her pelvic health. If you've ever wondered why sex is painful and what to do next, this is the most comprehensive and actionable explanation you’ve ever heard—all based entirely on the insights from the episode transcript. For full episode notes see: https://drbrighten.com/podcasts/pain-during-sex/ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Nov 27, 2025 • 53min

How Stress Causes Brain Damage: The New Science of Cortisol, Trauma, and Women’s Brains | Dr. Jessica Peatross

Most people think of traumatic brain injury (TBI) as something caused by a fall, car accident, or physical impact. But new research is redefining TBI entirely — and it has major implications for women. Emotional trauma, chronic stress, and prolonged cortisol elevation can create measurable changes in the brain that mimic the neurological patterns traditionally seen after concussions. In this episode, I sit down with Dr. Jessica Peatross to explore the emerging science of stress-induced brain injury, why women are uniquely affected, and how emotional trauma disrupts everything from neurotransmitter production to gut permeability to hormone balance. We also discuss Jessica’s personal experience: a cascade of traumatic events, B-vitamin deficiencies, functional freeze, personality changes, and escalating neurological symptoms that eventually led to the discovery of a right-sided brain injury. This Episode Is Brought to You By Dr. Brighten Essentials Radiant Mind—a science-backed formula created to support women’s brain health through every stage of life. If you’ve ever felt the brain fog of perimenopause or noticed how ADHD can amplify challenges with focus, memory, mood, or sleep, you’re not alone. Radiant Mind combines clinically studied saffron extract, Bacognize® Bacopa, Cognizin® Citicoline, and zinc to help nourish your brain chemistry and support clarity, calm, and resilience.  Shop now https://drbrighten.com/radiant/ Sunlighten Saunas Want a gentle, science-forward way to sweat, recover, and unwind?  At Sunlighten, infrared saunas deliver soothing heat that supports relaxation, muscle recovery, and deep, comfortable sweating—without the stifling temps of traditional saunas. With low-EMF tech and options for near, mid, and far infrared, you get a calm, restorative session tailored to your goals. Exclusive for podcast listeners: use the code DRBRIGHTEN to save up to $1,400 on your sauna Shop now https://get.sunlighten.com/drbrighten LUMEBOX Ready to take your skincare results to the next level—right from home? 💡 LUME Box delivers professional-grade LED light therapy in a sleek, easy-to-use device that targets fine lines, pigmentation, and dullness at the cellular level. Just minutes a day can help boost collagen, calm inflammation, and reveal that lit-from-within glow. It’s the same science trusted in top dermatology clinics, now in your hands. Shop now → https://drbrighten.com/lumebox use code drbrighten for our exclusive community discount on your purchase. ⭐ Follow Dr. Jessica Peatross: 💻  Website: https://drjessmd.com/ 📸  Instagram: https://www.instagram.com/dr.jess.md/?hl=en 👩🏻‍⚕️Follow Dr. Jolene Brighten: 💻 Website: https://www.drbrighten.com 📸  Instagram: https://www.instagram.com/drjolenebrighten 🎥 TikTok: https://www.tiktok.com/@drjolenebrighten 🧵Threads: https://www.threads.net/@drjolenebrighten 🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/ 🎧 Subscribe to the Podcast:  Apple: https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161 Spotify: https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417 YouTube: https://www.youtube.com/@drjolenebrighten 👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Nov 25, 2025 • 1h 9min

The Hidden Brain Risk Every Woman Over 30 Needs To Know | Max Lugavere

Women make up two out of three cases of Alzheimer’s disease, yet most are never told why—or what they can do to protect themselves long before symptoms appear. In this powerful conversation, Max Lugavere breaks down the misunderstood early drivers of cognitive decline, the role of metabolic health, how environmental toxins contribute to neurodegenerative diseases, and the research showing that the foods you eat every day can shift your brain’s trajectory decades before a diagnosis. If you’ve ever wondered why brain-related conditions disproportionately affect women, or whether prevention is actually possible, this episode is a must-listen. This Episode Is Brought to You By Dr. Brighten Essentials Radiant Mind—a science-backed formula created to support women’s brain health through every stage of life. If you’ve ever felt the brain fog of perimenopause or noticed how ADHD can amplify challenges with focus, memory, mood, or sleep, you’re not alone. Radiant Mind combines clinically studied saffron extract, Bacognize® Bacopa, Cognizin® Citicoline, and zinc to help nourish your brain chemistry and support clarity, calm, and resilience.  Shop now https://drbrighten.com/radiant/ Sunlighten Saunas Want a gentle, science-forward way to sweat, recover, and unwind?  At Sunlighten, infrared saunas deliver soothing heat that supports relaxation, muscle recovery, and deep, comfortable sweating—without the stifling temps of traditional saunas. With low-EMF tech and options for near, mid, and far infrared, you get a calm, restorative session tailored to your goals. Exclusive for podcast listeners: use the code DRBRIGHTEN to save up to $1,400 on your sauna Shop now https://get.sunlighten.com/drbrighten OneSkin  Founded by an all-woman team of PhD-level scientists, OneSkin is revolutionizing aging with the OS-01™ peptide, the first ingredient proven to reverse skin’s biological age by targeting cellular senescence. The result? Skin that looks, feels, and acts younger. It’s never too early — or too late — to invest in your skin health. Shop now https://oneskin.pxf.io/c/1950532/2885132/31050 🔥 Follow Max Lugavere: 💻 Website: https://www.instagram.com/maxlugavere/?hl=en 📸  Instagram: https://www.maxlugavere.com/ ⭕ Youtube: https://www.youtube.com/user/maxlugavere 👩🏻‍⚕️Follow Dr. Jolene Brighten: 💻 Website: https://www.drbrighten.com 📸  Instagram: https://www.instagram.com/drjolenebrighten 🎥 TikTok: https://www.tiktok.com/@drjolenebrighten 🧵Threads: https://www.threads.net/@drjolenebrighten 🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/ 🎧 Subscribe to the Podcast:  Apple: https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161 Spotify: https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417 YouTube: https://www.youtube.com/@drjolenebrighten 👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Nov 20, 2025 • 1h 34min

Why your PCOS Got WORSE after 30 and How to FIX it | Dr. Fiona McCulloch

Dr. Fiona McCulloch, a Naturopathic doctor and PCOS expert, dives into why PCOS symptoms often worsen after 30. She explains the interplay between insulin resistance, adrenal stress, and brain-ovary signaling, shedding light on the condition as a survival adaptation. Listeners learn about the significance of individualized nutrition, the role of inositol for hormone signaling, and the implications of prenatal influences. Dr. McCulloch also discusses the impact of lifestyle on insulin resistance and the importance of culturally sensitive care.

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