

The Dr. Brighten Show
Dr. Jolene Brighten
Dr. Jolene Brighten, a best-selling author, board certified naturopathic endocrinologist, and women’s health expert, hosts The Dr. Brighten Show—a podcast dedicated to igniting transformative conversations in women’s health. Through candid interviews with leading experts, innovators, and thought-leaders, this show brings you groundbreaking research, personal stories, and practical tools to help you confidently navigate your body and hormones. It’s a fun, engaging, and insightful journey designed to empower you with tangible, science-backed insights, so you can live your best, most vibrant life.
Episodes
Mentioned books

Nov 3, 2026 • 47min
Can Hypothyroidism Cause Weight Gain? Hashimoto’s, Thyroid Labs, and Muscle | Emily Kiberd
Emily Kiberd, chiropractor and founder of Thyroid Strong, joins a conversation on Hashimoto’s, hypothyroidism, and weight changes. They explore comprehensive thyroid testing, inflammation, sleep, protein, workout fueling, and building strength without overtraining. The discussion also covers gut tolerance, sustainable fat loss, muscle-focused goals, and practical starting points for women navigating thyroid health.

Oct 27, 2026 • 45min
ADHD Meltdown: The Spiral When Mom and Child Have ADHD | Psychiatrist's Advice
Agnes Kwon Simone, a board-certified psychiatrist focused on women’s mental health, and Ann-Louise Lockhart, a pediatric psychologist specializing in children and families, explore ADHD and motherhood. They discuss medication during pregnancy and postpartum, breastfeeding, executive-function overload, rejection sensitivity, and chaotic mornings. The conversation also covers co-regulation, repairing after parenting blowups, sharing the mental load, and creating more compassionate family systems.

Oct 20, 2026 • 1h 5min
ADHD Medication and Your Period: What Women Need to Know About Treatment, PMDD, and Changing Symptoms
Annika Joya, science communicator and author of The Eat to Focus Cookbook; Dr. Anne-Louise Lockhart, pediatric psychologist and author of Love the Teen You Have; and Dr. Agnes Kwan Simone, psychiatrist specializing in women’s mental health, explore ADHD treatment across the menstrual cycle. They discuss medication changes before periods, PMDD versus depression, nutrition, appetite crashes, therapy, stigma, and care during perimenopause.

Oct 13, 2026 • 1h 11min
Psychiatrists Warning: ADHD Relationships, Rejection Sensitive Dysphoria, and Building a Life That Works
Board-certified psychiatrist Agnes Kwon Simone, health psychology communicator Annika Angelo, and clinical sexologist Leann Borneman unpack ADHD in relationships. They explore mental load, rejection sensitivity, friendship struggles, novelty, intimacy, and desire. The conversation also tackles accountability, trauma, communication breakdowns, and practical systems for creating a life and relationships that fit an ADHD brain.

Oct 6, 2026 • 52min
ADHD and Hormones in Women: Why Symptoms Change Across Your Cycle and in Perimenopause | Agnes K. Simone & Annika Joya
Dr. Agnes K. Simone, a board-certified psychiatrist focused on women’s mental health, and Annika Joya, an ADHD nutrition researcher, explore how hormones shape ADHD in women. They discuss cycle-related focus changes, medication response, PMDD versus PME, masking and late diagnosis, nutrition, and why perimenopause can disrupt memory, mood, sleep, and executive function.

Sep 29, 2026 • 51min
ADHD in Women Symptoms: Why Success Can Hide the Signs
Leann Borneman, ADHD-focused psychotherapist and clinical sexologist; Ann-Louise Lockhart, pediatric psychologist; and Agnes Kwon Simone, psychiatrist specializing in women’s mental health, explore how ADHD can hide behind achievement. They discuss masking, uneven attention, emotional dysregulation, bias, and why quick screeners miss complex cases. The conversation also covers thorough evaluations, conditions that mimic ADHD, and advocating for support.

Sep 22, 2026 • 24min
Endometriosis and Perimenopause: Can You Use HRT? | Hormone Doctor's Warning
An insightful AMA explores why endometriosis and adenomyosis can intensify during perimenopause, along with the roles of inflammation, progesterone resistance, and shifting hormones. Topics include using HRT safely, alternatives to long-term progestins, natural support, surgery and ovarian preservation, fibroid treatments, fertility considerations, and concerns surrounding Lupron.

Sep 15, 2026 • 1h 18min
ADHD Rejection Sensitivity: Why Rejection Can Feel So Personal | Alex Partridge
Alex Partridge, entrepreneur, bestselling author, and ADHD awareness advocate, explores why rejection can feel overwhelming with ADHD. He discusses childhood criticism, masking, identity, emotional triggers, catastrophic thinking, people-pleasing, and rebuilding self-trust. The conversation also covers entrepreneurship, addiction, relationship repair, and protecting ADHD strengths such as creativity, intuition, and unconventional thinking.

Sep 8, 2026 • 1h 8min
Cellular Aging: Why Your Body May Be Aging Faster Than You Think | Dr. Will Cole
Cellular aging may be happening faster than your chronological age suggests—and in this episode, Dr. Will Cole explains what can accelerate it, what mitochondrial dysfunction can actually feel like, and what may help protect your healthspan; view the full show notes at https://drbrighten.com/podcasts/cellular-aging/. We break down the science of biological age, organ aging, inflammation, metabolic health, circadian rhythms, nutrition, movement, and practical longevity strategies you can actually use.
IN THIS EPISODE
Why people in their 20s, 30s, and 40s may be experiencing accelerated cellular aging
How your heart, brain, kidneys, and other organs can age at different rates
Why brain fog, fatigue, feeling wired-but-tired, and anxiety with exhaustion may be clues worth paying attention to
How inflammation and “cellular confusion” may affect mitochondrial function and aging
Which metabolic, cardiovascular, and inflammatory markers Dr. Cole considers clinically meaningful
How environmental toxins, microplastics, PFAS, stress, trauma, food, and artificial light may influence cellular health
The surprising conversation around nature, bird song, spirituality, community, and longevity
Why light exposure can disrupt more than sleep—your organs have their own cellular clocks
Why fatigue in women, including women with endometriosis, deserves to be taken seriously
How fasting, green tea, polyphenols, and meal timing fit into the longevity conversation
How to build a longevity-supportive plate without following a rigid wellness diet
Why a 10–15 minute walk after dinner may be one of the simplest metabolic tools available
Zone 2, REHIT, strength training, sauna, cold exposure, and mobility—what may actually be worth your time
And how to support healthier aging without turning wellness into a full-time job
ABOUT DR. WILL COLE
Dr. Will Cole is a functional medicine expert, New York Times bestselling author, and an early pioneer in functional medicine telehealth. In this conversation, he shares concepts from his newest book, Heal Your Cells, and explains the clinical lens he uses to think about inflammation, mitochondrial health, metabolic health, and longevity.
🌐 Dr. Will Cole: https://drwillcole.com
📘 Heal Your Cells: https://healyourcells.com
📸 Instagram: https://instagram.com/drwillcole
CONNECT WITH DR. JOLENE BRIGHTEN💛
🌐 Dr. Brighten: https://drbrighten.com
🎙️ The Dr. Brighten Show: https://drbrighten.com/podcasts
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THIS EPISODE IS BROUGHT TO YOU BY
✨ Dr. Brighten Essentials: https://drbrighten.com
🏷️ Use code POD15 where applicable.
📚 MENTIONED IN THIS EPISODE
📘 Heal Your Cells by Dr. Will Cole: https://healyourcells.com
🌐 Dr. Will Cole’s website + resources: https://drwillcole.com
🎙️ More episodes of The Dr. Brighten Show: https://drbrighten.com/podcasts
❤️ SUPPORT THE SHOW
👍 LIKE this episode if it gave you a new way to think about aging and cellular health.
💬 COMMENT below: What is one longevity habit you’re actually willing to start this week?
📤 SHARE this episode with someone who is constantly tired, dealing with brain fog, or wants to protect their health for the long term.
🔔 SUBSCRIBE to The Dr. Brighten Show for evidence-informed conversations about women’s health, hormones, brain health, metabolism, longevity, and the science that helps you better understand your body.
⚕️ This content is for educational purposes and is not a substitute for individualized medical care. Always discuss changes to your medications, supplements, fasting practices, or treatment plan with your healthcare professional. Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 1, 2026 • 43min
Perimenopause Hormone Therapy: What Women Need to Know About HRT, Progesterone & Estrogen
An AMA explores why perimenopause symptoms can feel intense even when lab results look normal. Topics include tracking ovulation, progesterone shifts, hormone testing, birth control versus HRT, Mirena, cyclic or continuous progesterone, estradiol and testosterone therapy, primary ovarian insufficiency, fertility awareness, exercise recovery, and the often-overlooked benefits of life after menopause.


