

The Dr. Brighten Show
Dr. Jolene Brighten
Dr. Jolene Brighten, a best-selling author, board certified naturopathic endocrinologist, and women’s health expert, hosts The Dr. Brighten Show—a podcast dedicated to igniting transformative conversations in women’s health. Through candid interviews with leading experts, innovators, and thought-leaders, this show brings you groundbreaking research, personal stories, and practical tools to help you confidently navigate your body and hormones. It’s a fun, engaging, and insightful journey designed to empower you with tangible, science-backed insights, so you can live your best, most vibrant life.
Episodes
Mentioned books

Sep 18, 2025 • 1h 33min
Peptides for Hair Loss & Skin Aging Reversal: OneSkin Review
Interested in trying OneSkin for yourself Visit http://oneskin.co/BRIGHTEN and use code BRIGHTEN for 15% off your first purchase.
Discover the best skincare products for aging skin and the science behind peptides that target “zombie cells” to support hair growth and skin longevity. View full show notes and all links at
https://drbrighten.com/podcasts/oneskin/.
Chapters — Key Moments
00:00 — Episode Trailer (Skin Aging Control)
01:24 — Show Welcome
02:12 — Topical Retinol & Inflammation
07:49 — How to Cycle Retinol Safely
10:48 — Zombie (Senescent) Cells Explained
14:28 — What Are Peptides?
16:55 — Not All Peptides Are Equal—OS01
17:19 — OS-01: Validated Results
22:09 — OneSkin Benefits Over Time
23:56 — OneSkin Review of Outcomes
25:37 — Menopause-Focused SkinCare
27:23 — How to Preserve Collagen
29:28 — Lowering Systemic Inflammation (Cytokines)
32:09 — Skin Fragility With Age
37:16 — Intrinsic vs. Extrinsic Aging
39:54 — Blue Light Damages Skin
40:58 — Best Antioxidants for Skin Health
43:45 — Smart Sun Exposure Guidelines
47:50 — Can You Reverse Sun Damage?
50:03 — Best Skincare Routine for Over 50
54:13 — Eye Cream Clinical Trial Results
55:58 — Best Skincare in Your 20s
57:13 — Pregnancy & Melasma Treatment
59:53 — Hidden Causes of Skin Aging
01:06:55 — Stress and Hair Loss
01:10:35 — How to Improve Hair Density & Thickness
01:15:18 — How to Regrow Hair
01:18:25 — Scalp Microbiome Health
01:23:51 — Biggest Skin-Aging Misconception
01:27:16 — Episode Outro
Dr. Brighten’s OneSkin Review
I always want to know if a product actually delivers on its promises before recommending it to my community. I tried OneSkin’s OS-01 peptide moisturizer and eye cream myself, and I was impressed. As someone with sensitive skin, I’m cautious with new products, but I noticed the eye cream made a real difference during a hectic back-to-school week when my sleep was lacking. My skin looked more hydrated and less tired than I felt.
What stood out most to me is that OneSkin’s peptide technology isn’t just about appearance—it’s about skin health and resilience. That’s what makes it different from many other products I’ve tested over the years. Learn more about your ad choices. Visit megaphone.fm/adchoices

4 snips
Sep 16, 2025 • 1h 37min
SIBO vs IBS vs Leaky Gut: Tests, Treatments, and How to Heal Fast | Dr. Carolina Gonzalez
If you’ve ever struggled with bloating, brain fog, or unexplained fatigue, you’ve probably wondered: Is it IBS, SIBO, or something else? In this episode of the Dr. Brighten Show, Dr. Jolene Brighten sits down with gut health powerhouse Dr. Carolina Gonzalez to uncover the truth about digestive disorders that are often misdiagnosed. They cut through the noise around parasite cleanses, leaky gut, and probiotics for SIBO—so you’ll know what really works, what doesn’t, and how to take the first steps toward true healing.
You’ll also learn why up to 70% of people told they have IBS actually have SIBO, how stress and sleep impact your microbiome, and what every woman should know about gut health, hormones, and long-term well-being.
This episode is brought to you by:
Dr. Brighten Essentials: https://drbrightenessentials.com use code POD15 for 15% off
Chorus: use this link http://chorusforlife.com/drbrighten and and receive 10 percent off your order or subscription
OneSkin: https://oneskin.pxf.io/c/1950532/2885132/31050
Support our sponsors and help keep this show free and packed with amazing guests!
🔗 Links & Resources Mentioned in This Episode:
Dr. Brighten Essentials Women’s Probiotic https://drbrightenessentials.com/products/womens-probiotic
Dr. Brighten Essentials Adrenal Calm https://drbrightenessentials.com/products/adrenal-calm
Carolina Gonzalez’s website https://www.ctnaturalhealth.com/
Carolina Gonzalez’’s Instagram: https://www.instagram.com/thegoodgutdoc/
Carolina Gonzalez’s Tik Tok: https://www.tiktok.com/@goodgutdoc
Podcast: Gut Health Probiotics https://drbrighten.com/podcasts/gut-health-probiotics/
Article: SIBO Part I https://drbrighten.com/sibo-symptoms-what-is-it-how-do-i-know-if-i-have-it/
Article: SIBO Part II: https://drbrighten.com/sibo-treatment-natural-diet/
Article: The Surprising Cause of IBS https://drbrighten.com/the-surprising-cause-of-ibs/
Article: Histamine Intolerance https://drbrighten.com/histamine-intolerance/
Podcast: Natural Treatments for Eczema | Jen Fugo https://drbrighten.com/podcasts/natural-treatments-for-eczema/
Podcast: Cortisol Face, Polycystic Ovarian Syndrome Insulin Resistance | Alaia Baldwin https://drbrighten.com/podcasts/cortisol-face/
Podcast: Hashimoto’s Hypothyroidism. Dr. Izabella Wentz https://drbrighten.com/podcasts/hashimotos-hypothyroidism/
Podcast: Top Foods That Delay Menopause | Dr. Kara Fitzgerald https://drbrighten.com/podcasts/how-to-delay-menopause/
Clean 15 & Dirty Dozen produce guide (EWG) https://www.ewg.org/foodnews/
👩🏻⚕️Follow Dr. Jolene Brighten:
💻 Website: https://www.drbrighten.com
📸 Instagram: https://www.instagram.com/drjolenebrighten
🎥 TikTok: https://www.tiktok.com/@drjolenebrighten
🧵Threads: https://www.threads.net/@drjolenebrighten
🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/
🎧 Subscribe to the Podcast:
Apple: https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161
Spotify: https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417
YouTube: https://www.youtube.com/@drjolenebrighten
👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 11, 2025 • 1h 39min
Menopause Brain Fog Is Real: 7 Science-Backed Ways To Clear It | Dr. Jolene Brighten
Menopause brain fog is the short-term difficulty with focus, word-finding, and memory that can show up in perimenopause and early postmenopause. It’s driven by estradiol fluctuations, declining progesterone/allopregnanolone (ALLO), and sleep fragmentation from hot flashes. The good news? It’s usually reversible with symptom treatment and daily habit shifts. Listen to this episode for the full brain-chemistry tour and a practical plan to feel clearer, calmer, and more you.
Chapters
00:00:00 Menopause Brain Fog: Who This Episode Helps
00:03:00 Perimenopause Timeline: 7–10 Years
00:06:00 Hormones that affect sleep
00:07:00 Women’s Testosterone: Drive, Initiation, Libido
00:09:00 HRT “Critical Window” + Insulin Resistance
00:11:00 Menopause Brain Fog Explained: “Software Update” Model
00:13:00 Endocrine Age vs Chronological Age: Why It Matters
00:14:00 My Story: Mood Crash & Lost Mental Edge
00:19:00 Menopause Brain Fog vs ADHD: Executive Function Clues
00:26:00 Hormone Stage Drives Brain
00:28:00 Estrogen, Dopamine, GABA: Memory & Focus Pathways
00:33:00 Signs to Look Out For
00:39:00 Hot Flashes Fragment Deep & REM Sleep (Here’s Why)
00:46:00 Will Brain Fog Go Away? SWAN Data & Adaptation
00:48:00 Medical Conditions That Cause Brain Fog
00:50:00 Focus Tools
00:55:00 Sleep Protocol: Fix Wake Time, Morning Light, Cool Room
00:57:00 Exercise & Brain Health
00:58:00 Saffron (Affron®): Mood, Sleep, Libido Support
01:01:00 Citicoline (Cognizin®): Attention & Mental Energy
01:04:00 Bacopa (Bacognize®): Memory & Calm Focus
01:08:00 Magnesium & Brain Health: Sleep, Migraines, Aging
01:18:00 Nervous System Downshift
01:22:00 CBT-I/ACT for Midlife Brain Fog & Rumination
01:23:00 Surgical Menopause & Dementia Risk
01:31:00 Key Takeaways
🎧For the entire show notes + links mentioned in the episode, please visit: https://drbrighten.com/podcasts/menopause-brain-fog/
👩🏻⚕️Follow Dr. Jolene Brighten:
💻 Website: https://www.drbrighten.com
📸 Instagram: https://www.instagram.com/drjolenebrighten
🎥 TikTok: https://www.tiktok.com/@drjolenebrighten
🧵Threads: https://www.threads.net/@drjolenebrighten
🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 9, 2025 • 1h 26min
Natural Treatments for Eczema That Actually Work: Creams, Moisturisers & More | Jen Fugo
Natural treatments eczema, eczema moisturisers, and dyshidrotic dermatitis—what actually helps and what quietly makes skin worse. View the full show notes and all links mentioned at https://drbrighten.com.
This episode is brought to you by:
Dr. Brighten Essentials
Use the Code: POD15 to save 15% on your order https://drbrightenessentials.com/
Chorus
Exclusive for podcast listeners: http://chorusforlife.com/drbrighten and and receive 10 percent off your order or subscription
OneSkin
Shop now → https://oneskin.pxf.io/c/1950532/2885132/31050
Links Mentioned in This Episode
Jennifer Fugo’s Healthy Skin Show Podcast https://podcasts.apple.com/us/podcast/the-healthy-skin-show/id1449210022
Quell Shop: Skincare and supplements for chronic skin conditions https://www.quellshop.com
Episodes Mentioned
Is It Really Histamine Intolerance? with Jen Fugo — on histamine, skin rashes, and hidden gut triggers https://drbrighten.com/podcasts/is-it-really-histamine-intolerance/
Struggling with Sleep & Anxiety? Dr. Carrie Jones https://drbrighten.com/podcasts/struggling-with-sleep-amp-anxiety/
The Best Skincare for Aging Skin| Dr. Sara Cherem https://drbrighten.com/podcasts/best-skincare-for-aging-skin/
The Best Skincare Products for Aging Skin| Dr. Tony Youn https://drbrighten.com/podcasts/best-skincare-products-for-aging-skin/
What Every Woman Needs to Know to Balance Hormones https://drbrighten.com/podcasts/gut-health-probiotics/
Articles:
What is Histamine Intolerance https://drbrighten.com/histamine-intolerance/
12 Natural Treatments for Hyperthyroidism https://drbrighten.com/natural-treatments-hyperthyroidism/
The Thyroid Gut Connection https://drbrighten.com/thyroid-gut-connection/
Topical Estrogen Face Cream https://drbrighten.com/estrogen-face-cream/
Studies & Research Mentions
Reviewing the Evidence Base for Topical Steroid Withdrawal Syndrome in the Research Literature and Social Media Platforms: An Evidence Gap Map: https://pmc.ncbi.nlm.nih.gov/articles/PMC11662184
Topical Steroid Withdrawal (Red Skin Syndrome): https://www.ncbi.nlm.nih.gov/books/NBK603718/
Topical Steroid Withdrawal in Atopic Dermatitis: Patient-reported Characterization from a Swedish Social Media Questionnaire: https://medicaljournalssweden.se/actadv/article/view/40187
Psoriasis https://www.nejm.org/doi/full/10.1056/NEJMra0804595
Interleukin-17 and Interleukin-23: A Narrative Review of Mechanisms of Action in Psoriasis and Associated Comorbidities https://pmc.ncbi.nlm.nih.gov/articles/PMC8019008
Proinflammatory Cytokine IL-17 Shows a Significant Association with Helicobacter pylori Infection and Disease Severity https://pmc.ncbi.nlm.nih.gov/articles/PMC5748147
Global Prevalence of Helicobacter pylori Infection and Incidence of Gastric Cancer Between 1980 and 2022 https://www.gastrojournal.org/article/S0016-5085%2823%2905687-1/fulltext
Global prevalence of Helicobacter pylori infection between 1980 and 2022: a systematic review and meta-analysis https://www.thelancet.com/journals/langas/article/PIIS2468-1253%2823%2900070-5/abstract
Revisiting the Roles of Filaggrin in Atopic Dermatitis https://pmc.ncbi.nlm.nih.gov/articles/PMC9140947
Filaggrin gene mutations with special reference to atopic dermatitis https://pmc.ncbi.nlm.nih.gov/articles/PMC7880084
Follow Jen Fugo:
💻 Website: https://www.jenniferfugo.com
📸 Instagram: http://www.instagram.com/jenniferfugo
💻 YouTube: https://www.youtube.com/jenfugo
🎥 TikTok: https://www.tiktok.com/@jenniferfugo
👩🏻⚕️Follow Dr. Jolene Brighten:
💻 Website: https://www.drbrighten.com
📸 Instagram: https://www.instagram.com/drjolenebrighten
🎥 TikTok: https://www.tiktok.com/@drjolenebrighten
🧵Threads: https://www.threads.net/@drjolenebrighten
🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 4, 2025 • 1h 19min
The Hidden Costs of People Pleasing: Why ADHD Women Struggle + How to Break Free | Meredith Carder
If you’ve ever found yourself saying “yes” when you desperately wanted to say “no,” you’re not alone—especially if you’re a woman living with ADHD. In this episode of The Dr. Brighten Show, I sit down with ADHD coach and author Meredith Carder to uncover why chronic people pleasing in ADHD women is so common, how it connects to masking, guilt, and burnout, and most importantly—how you can break free. You’ll hear practical tools, fresh perspectives, and science-backed insights that will make you feel seen, supported, and empowered.
This episode is brought to you by:
Dr. Brighten Essentials: https://drbrightenessentials.com use code POD15 for 15% off
Support our sponsor and help keep this show free and packed with amazing guests!
Links & Resources Mentioned in This Episode:
Meredith Carder – [Author & ADHD Coach] https://www.instagram.com/hummingbird_adhd/
Meredith’s community, The Hummingbird Hive https://meredith-rose-carder.mykajabi.com/group-membership
Meredith’s book It All Makes Sense Now https://amzn.to/45XHvTN
Research referenced: study on higher mortality risk in ADHD women
Dr. Ann Louise Lockhart’s episode on parenting and emotional regulation (for further listening) https://drbrighten.com/podcasts/raising-kids-with-big-feelings/
Diet for ADHD: How Nutrition Shapes Focus, Mood, and Brain Health | Timothy Frie https://drbrighten.com/podcasts/diet-for-adhd/
Mouth Breathing, ADHD & the Cavity Conspiracy: What Your Dentist Isn’t Telling You | Dr. Staci Whitman https://drbrighten.com/podcasts/mouth-breathing-in-children/
ADHD Types and Hormones: The Unexpected Link You Need to Know | Ludovico Saint amour di Chanaz https://drbrighten.com/podcasts/adhd-types-and-hormones/
ADHD, Sleep & Hormones: Why Your Brain Won’t Shut Off at Night https://drbrighten.com/podcasts/adhd-sleep-hormones/
ADHD Burnout? Your Hormones Might Be Sabotaging You https://drbrighten.com/podcasts/adhd-burnout/
How Hormones and Menopause Affect ADHD: What No One’s Telling You https://drbrighten.com/podcasts/menopause-and-adhd/
ADHD Endometriosis Connection: What You Should Know If You’re Diagnosed with ADHD https://drbrighten.com/podcasts/adhd-endometriosis-connection/
Article: Exploring Natural Solutions for Adult ADHD — How To Find Relief https://drbrighten.com/natural-remedies-adhd/
Follow Meredith Carder:
Website https://meredithcarder.com/
Instagram https://www.instagram.com/hummingbird_adhd/
Follow Dr. Jolene Brighten:
Website: https://www.drbrighten.com
Instagram: https://www.instagram.com/drjolenebrighten
TikTok: https://www.tiktok.com/@drjolenebrighten
Threads: https://www.threads.net/@drjolenebrighten
🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/
👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 2, 2025 • 2h 12min
Sjogrens Syndrome and Treatment: What Women Need to Know | Dr. Kara Wada
In this conversation, Dr. Jolene Brighten and quadruple–board-certified allergist & immunologist Dr. Kara Wada unpack why sjogren's disease is widely under-recognized, how “perfectionist” health habits can backfire into autoimmune flares, and exactly how to think about sjogren's treatment, testing, microbiome/barrier health, dysautonomia, POTS, MCAS, and smarter allergy therapies.
A sjogren’s test typically includes autoantibodies (SSA/SSB), but these are only ~60–70% positive, so diagnosis relies on the full picture: history, eye/dental findings, sometimes biopsy. Importantly, Sjögren’s carries a 5–10% lifetime risk of non-Hodgkin lymphoma, so persistent lymph nodes deserve prompt evaluation. Because labs can be “normal” while life isn’t, bring concrete examples of how symptoms limit your day, and ask for a plan that fits your stage of life (puberty, pregnancy, perimenopause).
This episode is brought to you by:
LUMEBOX
LUME Box delivers professional-grade LED light therapy in a sleek, easy-to-use device that targets fine lines, pigmentation, and dullness at the cellular level. Just minutes a day can help boost collagen, calm inflammation, and reveal that lit-from-within glow.
Shop now → https://drbrighten.com/lumebox use code drbrighten for our exclusive community discount on your purchase.
Dr. Brighten Essentials
At Dr. Brighten Essentials, every product is crafted to support your hormones, boost your energy, and help you feel your best—inside and out.
Exclusive for podcast listeners: Use code POD15 at checkout for 15% off your order.
Shop now → https://drbrightenessentials.com
Chorus
At Chorus, our Organic Gut Harmony formula is rooted in a 700-year-old botanical blend and updated with modern science to help your body thrive. From easing bloating and improving digestion to boosting energy and clarity.
Exclusive for podcast listeners: use this link http://chorusforlife.com/drbrighten and and receive 10 percent off your order or subscription
Links & Resources Mentioned in This Episode:
Sjögren’s Foundation (patient education & resources): https://www.sjogrens.org
Gut Hormone Connection Episode: https://drbrighten.com/podcasts/gut-health-probiotics/
Therapies discussed: Allergy shots; Sublingual immunotherapy (tablets/drops) and Intralymphatic immunotherapy (ILIT)
Medications referenced (discuss with your clinician): Hydroxychloroquine (Plaquenil); H1 antihistamines (e.g., loratadine, cetirizine); H2 blocker (famotidine); caution with diphenhydramine (Benadryl)
Research context named in the episode: LEAP trial (early oral peanut introduction): https://www.nejm.org/doi/full/10.1056/NEJMoa1414850
Follow Dr. Kara Wada:
💻 Website: https://drkarawada.com
📸 Instagram: https://www.instagram.com/immuneconfidentmd/
⭕ YouTube: https://www.youtube.com/@drkarawada
👩🏻⚕️Follow Dr. Jolene Brighten:
💻 Website: https://www.drbrighten.com
📸 Instagram: https://www.instagram.com/drjolenebrighten
🎥 TikTok: https://www.tiktok.com/@drjolenebrighten
🧵Threads: https://www.threads.net/@drjolenebrighten
🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/
🎧 Subscribe to the Podcast:
Apple: https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161
Spotify: https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417
YouTube: https://www.youtube.com/@drjolenebrighten
👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices

Aug 28, 2025 • 1h 2min
GLP-1 Weight Loss in Menopause: How HRT Amplifies Results
If your midlife metabolism suddenly stopped playing by the old rules, you’re not imagining it. In this episode, Dr. Brighten breaks down how perimenopause and menopause shift insulin sensitivity, fat distribution, appetite, and recovery and where glucagon-like peptide-1 (GLP-1) receptor agonists (think semaglutide/Ozempic, Wegovy, liraglutide, tirzepatide as a related incretin therapy) can fit safely alongside hormone therapy, lifting, protein, and smart lab work. You’ll leave with a practical checklist you can take to your clinician, plus a clear understanding of how to protect muscle, heart, and brain while losing fat.
Now, to be clear, this episode isn’t about convincing anyone to use a GLP-1. It is about making sure you know how they work, what the risks are, and what you MUST do to stay healthy on them. You’ll hear the new science of what role they play in cardiovascular disease prevention.
🎧For the entire show notes + links mentioned in the episode, please visit: https://drbrighten.com/podcasts/glp-1-weight-loss-in-menopause/
👩🏻⚕️Follow Dr. Jolene Brighten:
💻 Website: https://www.drbrighten.com
📸 Instagram: https://www.instagram.com/drjolenebrighten
🎥 TikTok: https://www.tiktok.com/@drjolenebrighten
🧵Threads: https://www.threads.net/@drjolenebrighten
🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/
👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices

Aug 26, 2025 • 1h 31min
Endometriosis, HRT, and Menopause: Expert Answers on Surgery, IVF & What Really Helps | Dr. Melissa McHale
Does endometriosis go away after menopause? Many women hope so, but the reality is more complex. In this episode of The Dr. Brighten Show, I sit down with Dr. Melissa McHale to unpack the latest science, surgical risks, and what women truly need to know about navigating endometriosis during perimenopause and menopause.
This Episode Is Brought to You By
LUMEBOX
💡 LUME Box delivers professional-grade LED light therapy in a sleek, easy-to-use device that targets fine lines, pigmentation, and dullness at the cellular level. Just minutes a day can help boost collagen, calm inflammation, and reveal that lit-from-within glow.
Shop now → https://drbrighten.com/lumebox use code drbrighten for our exclusive community discount on your purchase.
Dr. Brighten Essentials
At Dr. Brighten Essentials, every product is crafted to support your hormones, boost your energy, and help you feel your best—inside and out.
Exclusive for podcast listeners: Use code POD15 at checkout for 15% off your order.
Shop now → https://drbrightenessentials.com
Sunlighten Saunas
At Sunlighten, infrared saunas deliver soothing heat that supports relaxation, muscle recovery, and deep, comfortable sweating—without the stifling temps of traditional saunas.
Exclusive for podcast listeners: use the code DRBRIGHTEN to save up to $1,400 on your sauna
Shop now → https://get.sunlighten.com/drbrighten
Links & Resources Mentioned in This Episode
Dr. Melissa McHale’s clinic: https://www.washingtonendometriosis.com/
Dr. Melissa McHale’s social media: https://www.instagram.com/drmelissamchale/?hl=en
Endo Flare guide https://drbrighten.com/endoflare/ to help you get of, and stay out of pain
Beyond the Pill (Book) https://drbrighten.com/beyond-the-pil
Is This Normal (Book) https://drbrighten.com/is-this-normal
ADHD and Endometriosis Connection https://youtu.be/M57eI4uA2A0?si=K-T1hLA7bSppRO3d
When to Take Progesterone for Perimenopause https://drbrighten.com/progesterone-for-perimenopause/
Menopause and Autoimmune Disease in Women: Symptoms, Flare-Ups, and What Your Doctor Isn’t Telling You https://drbrighten.com/menopause-and-autoimmune-disease/
Pelvic Congestion Syndrome, Interstitial Cystitis, & Chronic Pelvic Pain (CPPS Disease): How to Finally Get Relief | Dr. Ana Sierra https://drbrighten.com/podcasts/pelvic-congestion-syndrome/
How to Tell If You Have Endometriosis. Painful Menstruation, Symptoms, and Treatment | Dr. Ramiro Cabrera https://drbrighten.com/podcasts/how-to-tell-if-you-have-endometriosis/
Endometriosis Awareness Month: Shttps://drbrighten.com/podcasts/symptoms-of-menopause/Fassbender A, Vanhie A, Saunderpecial Episode Clips https://drbrighten.com/podcasts/endometriosis-awareness-month-special-episode-clips/
Should You Consider HRT? How to Know If It's Time & What to Ask Your Doctor https://drbrighten.com/podcasts/should-you-consider-hrt/
HRT for Menopause & Perimenopause: Benefits, Side Effects & Menopause Solutions | Dr. Amy Killen https://drbrighten.com/podcasts/hrt-for-menopause/
The Medical System Is Misleading Women About Symptoms of Menopause | Dr. Tara Scott s PTK, et al. Endometriosis and cancer: lessons from a clinico-pathological and molecular approach https://pmc.ncbi.nlm.nih.gov/articles/PMC10046182/pdf/cancers-15-01708.pdf Cancers (Basel). 2023;15(6):1708. doi:10.3390/cancers15061708
✨ Stay Connected with Dr. Brighten ✨
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Learn more about your ad choices. Visit megaphone.fm/adchoices

Aug 21, 2025 • 49min
Progesterone Side Effects & Intolerance: Why You Feel Worse on Progesterone | Dr. Jolene Brighten
So you finally got your progesterone prescription to help you sleep better, feel calmer, and support your hormones, but instead of feeling better, you’re more anxious, moody, and wide awake at night. You might have progesterone intolerance.
In this episode of The Dr. Brighten Show, I uncover why some women experience the opposite of the “calming” benefits they’re promised, and what new research reveals about how progesterone interacts with the brain. Whether you’re in perimenopause, on HRT, or struggling with PMS/PMDD, this conversation will help you finally connect the dots.
Understanding Progesterone Intolerance and Side Effects
What are the side effects of progesterone? Progesterone side effects can include insomnia, panic attacks, mood swings, and even feelings of rage. For many women, though, it has the opposite effect—improving sleep and calming the nervous system. In this episode https://drbrighten.com/podcasts/struggling-with-sleep-amp-anxiety/ , I share the science behind why some women thrive while others struggle.
Can progesterone cause anxiety? Yes, in some women. Instead of activating the brain’s calming GABA receptors, progesterone’s metabolite may overstimulate the nervous system. I explain how new research on the amygdala sheds light on this paradox.
Is progesterone intolerance the same as PMS or PMDD? Not quite. While symptoms can overlap, progesterone intolerance has unique brain-level differences that make women more reactive during the luteal phase. Tune in to hear the distinctions that matter for treatment.
What’s the difference between progesterone and progestin side effects? Doctors and media often use these words interchangeably, but they aren’t the same. Progestins are synthetic, bind differently to hormone receptors, and are linked with depression risk in teens and women starting contraception. I break down the chemistry and clinical differences in this episode https://drbrighten.com/podcasts/struggling-with-sleep-amp-anxiety/.
For the entire show notes + links mentioned in the episode, please visit: https://drbrighten.com/podcasts/progesterone-side-effects/
Book: Is This Normal? by Dr. Jolene Brighten – https://drbrighten.com/is-this-normal
Book: Beyond the Pill by Dr. Jolene Brighten – https://drbrighten.com/beyond-the-pil
Progesterone Intolerance Article – https://drbrighten.com/progesterone-intolerance
Dr. Brighten Essentials Supplements:
Adrenal Calm – https://drbrightenessentials.com/products/adrenal-calm
Adrenal Support – https://drbrightenessentials.com/products/adrenal-support
Women’s Probiotic – https://drbrightenessentials.com/products/womens-probiotic
Balance Women’s Hormone Support – https://drbrightenessentials.com/products/balance
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Aug 19, 2025 • 1h 29min
Sugar and Brain Health: How Diet Shapes Kids’ Focus, Mood & Microbiome | Dr. Elisa Song
Are you unknowingly feeding your kids foods that sabotage their gut health, disrupt hormones, and even affect brain performance? In this eye‑opening conversation, I sit down with pediatric functional medicine expert Dr. Elisa Song to uncover the hidden ingredients and environmental exposures shaping your child’s mood, focus, immune health, and long‑term development. From sugar and brain function to delayed puberty in boys, autoimmune warning signs, and the microbiome’s role in behavior, this is a must‑listen for every parent who wants to protect and optimize their child’s health.
This is our second episode with Dr. Elisa Song, so be sure to check out our first interview where we talked extensively about strategies for picky eaters https://drbrighten.com/podcasts/child-gut-health/
This episode is brought to you by:
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Dr. Brighten Essentials
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Support our sponsors and help keep this show free and packed with amazing guests!
🔗 Links & Resources Mentioned in This Episode:
Dr. Elisa Song’s website https://www.healthykidshappykids.com
Dr. Elisa Song’s Book Healthy Kids, Happy Kids: An Integrative Pediatrician’s Guide to Whole Child Resilience https://amzn.to/3EsfeuI
https://drbrighten.com/ for nutrition, hormone, and fertility support
Dr. Brighten Essentials Women's Probiotic for mom’s microbiome https://drbrightenessentials.com/products/womens-probiotic
Tiny Health– gut microbiome testing https://www.tinyhealth.com/
Episode with dentist Stacey Whitman https://drbrighten.com/podcasts/mouth-breathing-in-children/ about oral health/the oral microbiome
⭐ Follow Dr. Elisa Song:
💻 Website: https://www.healthykidshappykids.com
📸 Instagram: https://www.instagram.com/healthykids_happykids/
🟦 Facebook: https://www.facebook.com/DrElisaSongMD/
👩🏻⚕️Follow Dr. Jolene Brighten:
💻 Website: https://www.drbrighten.com
📸 Instagram: https://www.instagram.com/drjolenebrighten
🎥 TikTok: https://www.tiktok.com/@drjolenebrighten
🧵Threads: https://www.threads.net/@drjolenebrighten
🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/
👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨ Learn more about your ad choices. Visit megaphone.fm/adchoices