Nutrition Facts with Dr. Greger
Why Do Most Users Quit Ozempic?
Apr 24, 2025
The podcast delves into the complexities surrounding Ozempic, highlighting why many users struggle to maintain weight loss after starting the medication. It critiques the pharmaceutical industry's pricing strategies while examining the health impacts and challenges of staying on Ozempic. Key reasons for discontinuation, such as side effects, are discussed, inviting listeners to share their personal experiences and promoting resources for evidence-based nutrition.
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Quick takeaways
- Ozempic's effectiveness diminishes over time as users often face a rebound in hunger and return to pre-treatment weight levels.
- The high cost of Ozempic creates a significant barrier to access and raises concerns about its long-term cost-effectiveness compared to sustainable lifestyle changes.
Deep dives
Challenges of Ozempic and Weight Loss Plateau
Ozempic and similar anti-obesity medications do not yield consistent results for all users, often leading to a weight loss plateau after about a year. Despite initial success in reducing appetite through increased GLP-1 activity, users may experience a rebound in hunger as the body adapts to weight loss. This physiological resistance diminishes the appetite-suppressing effects of the drug, resulting in a situation where caloric intake can match caloric expenditure, halting further weight loss. Ultimately, many users may find themselves in a similar weight category to where they started, as their metabolism responds to previous weight loss efforts, whether through diet, medication, or surgical intervention.
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