

August Q&A - Episode 299
In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Steve Reiter explore various aspects of longevity, including organ age testing, the pace of aging, multi-drug gerotherapy, the role of GLP-1s, gene therapy, and the importance of lifestyle choices in optimizing health and longevity. They discuss innovative testing methods to assess organ health, the implications of aging rates, and the potential of new therapies to enhance longevity. The conversation emphasizes the significance of understanding individual health metrics and making informed lifestyle choices to achieve optimal health outcomes.
For Audience
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Takeaways
· Every organ has its own age, impacting overall health.
· Understanding organ age can help tailor longevity strategies.
· New tests can predict health risks before they manifest.
· Multi-drug gerotherapy offers a new approach to aging.
· GLP-1s have benefits beyond weight loss, including heart health.
· Gene therapy may offer new avenues for reversing aging.
· Lifestyle factors remain crucial for longevity and health.
· Regular sauna use significantly reduces all-cause mortality.
· Testing and monitoring are essential for personalized health.
· Combining therapies can enhance the effectiveness of treatments.
Chapters
00:00 Introduction to Age Hacking and Organ Age Testing
01:26 Understanding Organ Age and Proteomic Testing
07:58 The Pace of Aging and Longevity Insights
12:54 Senolytics and Multi-Drug Gerotherapy
23:53 Cleaning the System for Regenerative Therapies
25:46 Rejuvenation Factors and Supplements
26:02 Exploring GLP-1s Beyond Weight Loss
34:39 Gene Therapy and Epigenetic Reprogramming
45:36 Lifestyle Science and Hormesis
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Gladden Longevity Podcast Disclosures
- Production & Independence
The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden’s clinical practice and research at Gladden Longevity in Irving, Texas.
Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.
- Medical Disclaimer
The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.
The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.
Use of information from this podcast and any linked materials is at the listener’s own risk.
- Podcast Guest Disclosures
Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.
- Sponsorships & Affiliate Disclosures
To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.
We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.
- Additional Note on Content Integrity
All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.