Science Spotlight #1: Dr. Anurag Singh on Mitochondria and Aging (S12E17)

In this inaugural Science Spotlight episode of 2025, Dr. Lee Warren dives deep into the world of mitochondrial health. He introduces the concept of 'Mitochondria Monday,' focusing on the importance of maintaining mitochondrial function for longevity and wellness as we age. Joined by Dr. Anurag Singh from Switzerland, an expert in cellular regeneration and mitochondrial health, they discuss the role of mitophagy, the groundbreaking molecule urolithin A, and its potential to rejuvenate and repair cells. The discussion includes the latest scientific findings, practical health tips, and an introduction to MitoPure, a product from Dr. Singh's company, Timeline, aimed at enhancing mitochondrial function. This episode provides valuable insights into how to proactively nurture your body for improved health and longevity.

Click here for the computer-generated transcript

Chapters

00:00 Introduction to 2025 and Science Spotlights

00:34 Understanding Mitochondria

01:14 The Aging Process and Mitochondria

02:57 Introducing Urolithin A

04:48 Interview with Dr. Anurag Singh

05:23 Dr. Singh's Background and Research

09:15 Mitochondria and Aging

12:32 Gut Health and Mitochondria

15:01 Urolithin A and Muscle Health

19:49 Brain Health and Urolithin A

25:49 Timeline and MitoPure Products

31:26 Conclusion and Health Tips

This episode was sponsored by Timeline.

Mitochondrial dysfunction as we age has been linked to muscle dysfunction, metabolism, overall energy levels, and resiliency. But what makes our mitochondria fail as we get older? It turns out to be related to a disruption in a process called mitophagy, the natural repair and recycling process that normally rebuilds and recreates healthy mitochondria to replace damaged ones. When mitophagy fails, mitochondria lose efficiency and cannot do their jobs, and we have a power failure. The compound that's key to keeping mitophagy happening normally is called Urolithin-A, and that compound is lacking in most of us because of a change over time in our gut microbiota. Timeline is renewing this process and making our mitochondria better with their product Mitopure. It will help you repair your cells, increase your strength, and become healthier. Check it out at timeline.com, and use the discount code leewarren33 for 33% off your first order.

Resources and Links:

• Journaling is a helpful tool to specifically lay out your BRAIN goals, the action steps you need to reach them, and keep track of your progress. I use this PRODUCTIVE WEEKS planner* to map out my projects, podcasts, and books. I used it every day in 2024 as I sketched out and wrote my upcoming book, The Self-Brain Surgery Handbook.
• I’ve created a free BRAIN Goals™ Guide for you! Click here to download the guide. It will help you align your mindset to your mission and set goals to make 2025 your best year yet!
• Be sure to check out my latest book, Hope Is the First Dose!
• Sign up for my weekly Self-Brain Surgery Newsletter here!

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