Incubation cover image

Incubation

Measles: The Cancer Killer?

Nov 26, 2024
Michael Mina, a former Harvard epidemiologist and current chief scientific officer at eMed, reveals the surprising impact of measles on the immune system, leading to what's called 'immune amnesia.' He discusses how measles can weaken immune responses and increase vulnerability to other diseases. Stephen Russell, co-founder of Vyriad and a former Mayo Clinic researcher, shares innovative approaches using the measles virus to target cancer cells, exploring this exciting frontier of virotherapy and its potential benefits for cancer treatment.
29:41

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Recent research shows that measles causes 'immune amnesia', significantly compromising children's immune memory and increasing susceptibility to other infections.
  • The potential of using the measles virus in oncolytic virotherapy suggests innovative cancer treatment possibilities through its ability to target cancer cells.

Deep dives

The Unexpected Consequences of Measles

Measles has been found to have significant effects on the immune system beyond the immediate symptoms of fever and rash. Recent research indicates that measles infections can lead to a phenomenon termed 'immune amnesia', where children lose a significant portion of their immune memory after recovering from the disease. This loss makes them more susceptible to other infections for an extended period, resulting in increased mortality rates from diseases unrelated to measles. The data show that after measles outbreaks, there was a corresponding rise in deaths from other infectious diseases, suggesting that measles may disrupt the immune system's ability to fight off previously encountered pathogens.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode