Oncotarget
Melatonin in Cancer Therapy: Lessons From 50 Years of Research
Dec 29, 2023
The podcast explores the potential of melatonin as a treatment for cancer, discussing its effects on tumor growth, anti-cancer therapies, metastasis, and inflammatory processes. It also delves into the mechanisms and clinical applications of melatonin in cancer treatment, emphasizing the importance of timing and the need for further research.
08:25
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Quick takeaways
- Melatonin demonstrated inhibitory effects on mammary tumors, leading to further research on its anti-cancer properties.
- Melatonin can enhance the efficacy of cytotoxic therapy and alleviate side effects in mice models.
Deep dives
The inhibitory effect of melatonin on transplantable mammary tumors in mice
The groundbreaking study conducted by Vladimir Anandissimov and his co-authors in 1973 demonstrated the inhibitory effect of melatonin on transplantable mammary tumors in mice, laying the foundation for subsequent investigations into melatonin's anti-cancer properties.
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