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The Readout Loud

320: Jim Wilson's next venture, a surprise startup shutdown, & Lilly's Zepbound strategy

Aug 29, 2024
In this engaging discussion, gene therapy pioneer Jim Wilson, known for his groundbreaking work at the University of Pennsylvania, shares insights on his recent departure and future plans. Joining him is Jonathan Wosen, a biotech reporter, who sheds light on the surprising closure of a gene editing company and the challenges facing the industry. They explore Eli Lilly's new pricing strategy for its obesity drug, Zepbound, and the shift toward direct-to-consumer sales. The conversation captures the dynamic, often unpredictable nature of biotech today.
37:34

Podcast summary created with Snipd AI

Quick takeaways

  • Jim Wilson's exit from the University of Pennsylvania reflects the challenges and funding declines impacting the gene therapy field.
  • The collapse of gene editing startup Tome illustrates the volatile nature of biotech investments and shifting investor sentiment in the sector.

Deep dives

Jim Wilson Leaves UPenn Amid Industry Funding Challenges

Jim Wilson, a pioneer in gene therapy, is departing from the University of Pennsylvania due to a significant decrease in industry funding for academic research and various challenges within the gene therapy sector. After years of generating substantial revenue through partnerships, Wilson noted a drastic shift where obtaining funding became increasingly difficult. His departure marks the end of a successful yet turbulent era, characterized by lucrative licensing deals and the establishment of numerous biotech companies. He aims to transition his work into two newly formed companies, reflecting a strategic shift to tackle issues in the worsening funding environment for research.

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