The Clinical Problem Solvers Episode 393 – Spaced Learning Series – Hyperglycemia
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May 1, 2025 Dive into a gripping case of hyperglycemia that might hide something more sinister. The hosts dissect a 65-year-old patient’s alarming symptoms, linking them to potential pancreatic cancer risks. They tackle diagnostic nuances like insulin resistance and the complexities of lab results, including the dangers of hypokalemia. Personal anecdotes and sharp medical insights illuminate the discussion, while the importance of early diagnosis and thorough patient history is emphasized throughout.
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Mukund's Diagnostic Reasoning Approach
- Mukund asked insightful questions to analyze hyperglycemia causes from a simple clinical presentation.
- He applied clinical schemas connecting insulin deficiency and resistance to patient scenarios for diagnostic reasoning.
New Diabetes May Signal Cancer
- New onset diabetes with rapid weight loss and smoking history heightens suspicion for pancreatic cancer.
- Epigastric pain plus polyuria and constipation are clues beyond typical type 2 diabetes features.
Differentiate Diabetes Mechanisms Carefully
- Distinguish diabetes caused by insulin deficiency versus insulin resistance by evaluating symptom timing and insulin response.
- Hypokalemia presence signals catabolic state likely from insulin deficiency needing careful potassium management before insulin.
