

Oprah and Dr. Ania Jastreboff on How People Treat You Differently After Weight Loss
Jan 21, 2025
Dr. Ania Jastreboff, an expert in obesity treatments from Yale, and Dr. Rachel Goldman, a clinical psychologist from NYU, discuss the transformative effects of GLP-1 medications on both physical health and mental well-being. They dive into personal stories of individuals who experienced significant weight loss and the stark shift in how they're treated socially. The conversation sheds light on the emotional complexities tied to body image and identity, as well as the need for greater understanding of obesity as a disease impacting both healthcare and societal perceptions.
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Brian's Transformation
- Brian Piotrowicz, a producer, initially hesitated to try GLP-1s, fearing side effects and mourning food.
- Oprah's question, "What are you waiting for?", prompted him to start, resulting in 70 pounds lost in five months.
Visibility After Weight Loss
- Oprah and Brian discuss how people treat him differently after weight loss.
- Brian notes increased eye contact, friendlier interactions, and more conversations initiated by strangers.
Weight Loss Medications: Still Emerging
- Only 12% of Americans have taken a weight loss medication, although half would like to.
- Oprah normalized the conversation around GLP-1s by publicly sharing her experience.