Could Ozempic Help Alzheimer's with Dr. Richard Isaacson

May 6, 2025

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This week, Kim and I have a vulnerable discussion about my risk of Alzheimer’s Disease. Three of my four grandparents, my late father, and my mother have all struggled with Alzheimer’s and dementia. As I have grown older, the fear of developing it has always been in the back of my mind. But I have something all of my family didn’t - new information on how to TRY to prevent it.

We are honored to have Dr. Richard Isaacson join us and share his research as one of the leading voices in Alzheimer’s disease prevention. Dr. Richard Isaacson is Director of Research at The Institute for Neurodegenerative Diseases (IND) and Director of the Precision Prevention Program at Atria Health and Research Institute. His research explores how lifestyle interventions can help reduce the risk of Alzheimer’s. We discuss everything from how Ozempic may help to what supplements not to take. I also try to keep things light with the "Top 5 Funniest Things About Alzheimer’s" at the end of the show (and Kim gives a #NotSponsored endorsement and update on her Road To 50!)

Have you been personally impacted by Alzheimer’s? We would love to hear what you think! Leave us a voicemail at 323-364-3929 or write the show at podcast@theholdernessfamily.com. You can also watch our podcast on YouTube.

Check your Omega-3 levels at omegaquant.com

Address specific risk factors at retainyourbrain.com

Find free resources and donate to Dr. Isaacson's research at IND.org

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Laugh Lines with Kim & Penn Holderness is an evolution of The Holderness Family Podcast, which began in 2018. Kim and Penn Holderness are award-winning online content creators known for their original music, song parodies, comedy sketches, and weekly podcasts. Their videos have resulted in over two billion views and over nine million followers since 2013. Penn and Kim are also authors of the New York Times Bestselling Book, ADHD Is Awesome: A Guide To (Mostly) Thriving With ADHD and winners on The Amazing Race (Season 33) on CBS.

Laugh Lines is hosted and executive produced by Kim Holderness and Penn Holderness, with original music by Penn Holderness. Laugh Lines is also written and produced by Ann Marie Taepke, and edited and produced by Sam Allen. It is audio engineered by Max Trujillo and hosted by Acast. Thanks for listening!

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