Rena Malik, MD Podcast: Optimizing Health, Sex & Relationships with Science Backed Tips from Leading Experts Moment: Reverse Erectile Dysfunction Permanently?! New Therapies to Make it Rock Hard (for good?)
Sep 17, 2025
Dr. Mohit Khera, a urologist specializing in male sexual dysfunction, joins the discussion on revolutionary therapies for erectile dysfunction. They delve into hyperbaric oxygen and shockwave therapy, underlining their promising yet cautious application. The pair also examine the potential of radiofrequency technology and investigational therapies like stem cells and PRP. Insights into Botox's role and the importance of patient counseling are explored, making it clear that while hope is on the horizon, thorough research is still essential.
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Hyperbaric Oxygen Has A Plausible Regenerative Role
- Hyperbaric oxygen may trigger regenerative growth by mimicking intermittent hypoxia and releasing growth factors.
- Hospital-grade chambers reach pressures home units don't, so home devices likely underdeliver.
Check The Shockwave Machine Type First
- Verify the shockwave device type before treatment and prefer electrohydraulic or electromagnetic systems.
- Expect an investigational outcome and counsel patients about placebo rates and variable efficacy.
First U.S. Stem Cell Trial Had Temporary Gains
- Mohit Khera described running the first U.S. stem cell trial for ED using liposuction-derived cells and injections.
- The effect was real but faded after six to nine months, making repeat invasive procedures impractical.