Science Vs Introducing The Journal: Trillion Dollar Shot
11 snips
Jun 11, 2024 
The podcast explores the business story behind blockbuster drugs like Ozempic for weight loss. It focuses on the Novo Nordisk scientist who invented the compound paving the way for Ozempic. It discusses the development, impact, and challenges faced in the pharmaceutical market and the affordability issues related to weight loss medications.
AI Snips
Chapters
Transcript
Episode notes
Brad Olson's Weight Loss Journey
- Brad Olson shared his personal experience of taking Mount Jaro for weight loss, losing about 40 pounds in five months.
- He described how the medication silenced disruptive hunger cravings, making weight loss easier than ever before.
GLP-1 Drug Development Breakthrough
- Lada Knudsen led the development of liraglutide by making GLP-1 long-acting, solving the problem of its rapid breakdown.
- The compound stayed in the body 24 hours, paving the way for Ozempic's scientific foundation.
Proof of Concept for GLP-1 Drugs
- Approval of liraglutide (Victoza) in 2010 marked a decade-long milestone proving the GLP-1 class could become effective drugs.
- This success validated the approach and inspired further development of more potent successors.