This first Podcast for the Neurology Journal begins with Dr. John H. Noseworthy, Editor-in-Chief briefly discussing highlighted articles from the print issue of Neurology. In the second segment, Dr. Ted M. Burns and Dr. Karen Roos interview Dr. Frederick Blanc from France about his paper on antibody index testing for Lyme disease. The podcast concludes with Dr. Ted M. Burns providing an overview and background of the Neurology podcast initiative and an introduction to the podcast committee and other upcoming initiatives for future podcasts.