Incubation
Polio: The Last Mile
Sep 14, 2023
Learn about the challenges in eradicating polio, the rivalry between scientists Albert Sabin and Jonas Salk, and the successful efforts to eradicate polio in India. Also, explore the development of accurate protein replicas of the polio virus and the effectiveness of the Orexv vaccine.
27:32
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Quick takeaways
- The development of polio vaccines involved a scientific rivalry between Jonas Salk and Albert Sabin, with Salk creating a killed virus vaccine and Sabin developing an attenuated virus vaccine.
- India successfully stopped transmission of polio and maintained a polio-free status for 12 years by reaching every child under five with two drops of the oral vaccine, demonstrating the principles of global health eradication.
Deep dives
The Development of Polio Vaccines: Salk and Sabin
This podcast episode explores the story of the scientific rivalry between Jonas Salk and Albert Sabin in the development of polio vaccines. Salk focused on creating a killed virus vaccine, while Sabin chose to develop an attenuated virus vaccine. Salk's vaccine proved to be safe and effective, leading to a successful vaccination campaign in the US. However, Sabin's vaccine, which was cheaper and easier to administer orally, was widely used in other parts of the world. Ultimately, both vaccines played a crucial role in eradicating polio.
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