The Optispan Podcast with Matt Kaeberlein

Answering Questions on Gold Standard Longevity Intervention RAPAMYCIN | 47 - AMA #4

Jul 9, 2024
Exploring the impacts of Rapamycin on diseases and biological aging, optimizing drug dosing for efficacy, discussing blood serolimus levels and potential effects on bone health, comparing SGLT2 inhibitors with Rapamycin for longevity intervention, and highlighting the use of Rapamycin for immune system restoration and heart health in aging animals.
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INSIGHT

Rapamycin's Potential

  • Rapamycin has shown broad positive effects on age-related diseases in animal studies.
  • Human studies are lacking, but anecdotal reports and specific-use cases suggest potential benefits.
INSIGHT

Lifespan in Primates

  • Recent research indicates rapamycin extends lifespan in marmosets, a non-human primate.
  • This strengthens the possibility of similar effects in humans, as primates are biologically closer than rodents.
ADVICE

Dietary Consistency

  • Maintain a consistently healthy diet regardless of rapamycin intake.
  • Don't overthink dietary changes on rapamycin days; current understanding is limited.
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