The Clinical Problem Solvers Episode 360: Schema Episode – Nephrotic Syndrome
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Oct 16, 2024 Dive into the intricacies of nephrotic syndrome through a captivating case study. Explore the complexities of diagnosing leg edema and the challenges of heart failure with preserved ejection fraction. Discover how integrating lab results and patient histories enhances diagnosis. Learn about the importance of schemas in medical education, alongside the latest advances in kidney pathology diagnostics, such as the role of the PLA2R antibody. Celebrate personal milestones and reflections on friendships within the medical community.
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Red Leg Differential
- Consider if leg redness is unilateral or bilateral, as this changes the differential diagnosis.
- Unilateral suggests a local process, while bilateral suggests a systemic process like venous stasis or volume overload.
Cellulitis Mimics
- Cellulitis misdiagnosis is very common, with a systematic review finding 39% misdiagnosis rate.
- Mimics include venous stasis dermatitis, gout, abscesses, and osteomyelitis.
Edema Differential
- For lower extremity edema, consider causes like increased hydrostatic pressure (heart failure, CKD) and venous stasis or lymphedema.
- Also, consider decreased capillary oncotic pressure (nephrotic syndrome, cirrhosis).