JAMA Clinical Reviews

JAMA Editors’ Choice 2024: Clinical Reviews Podcasts

27 snips
Jan 2, 2025
Robert Kushner, a renowned author and professor at Northwestern University's Feinberg School of Medicine, dives into the latest advancements in obesity treatment. He discusses new FDA-approved medications, such as semaglutide and terzepatide, highlighting their effectiveness and side effects. Kushner emphasizes the importance of treating obesity as a chronic disease, the potential implications of stopping medication, and the need for gradual dose adjustments. This insightful conversation sheds light on the evolving landscape of obesity management.
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ADVICE

Managing Side Effects of Obesity Medications

  • Slowly increase medication dosage to minimize gastrointestinal side effects like nausea and diarrhea.
  • Counsel patients on a healthy diet with smaller, low-fat meals and hydration.
INSIGHT

Long-Term Use of Obesity Medications

  • Suddenly stopping anti-obesity medications leads to significant weight regain.
  • Research explores alternative strategies like intermittent use or dose reduction.
ADVICE

Long-Term Obesity Management

  • Consider obesity a chronic disease requiring long-term treatment like diabetes or hypertension.
  • Continue medication if tolerated and effective, but explore alternative medications or strategies.
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