Talking Sleep

Defining Well Treated Obstructive Sleep Apnea

Feb 21, 2025
Barry Krakow, a sleep medicine physician known for work on treatment‑resistant insomnia and advanced PAP therapy, discusses measuring success in obstructive sleep apnea beyond simple numbers. He covers switching from CPAP to bilevel/ASV for flow limitation, links between sleep fragmentation and anxiety/PTSD, insurer negotiation for advanced devices, and behavioral tricks to improve PAP tolerance.
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INSIGHT

Subjective 'Better' Can Mask Incomplete Treatment

  • Many patients on CPAP report feeling 'better' but aren't reaching a true physiological ceiling of normal sleep.
  • Barry Krakow found switching to bilevel or ASV often corrected persistent flow limitation and produced noticeably better results.
ANECDOTE

Personal Turnaround After Switching To Bilevel

  • Krakow recounts switching many patients from CPAP to bilevel and watching dramatic clinical improvement.
  • He describes personally feeling the difference when he switched from CPAP to bilevel himself.
ADVICE

Retitrate For Flow Limitation Before Increasing Pressure

  • Bring patients back to the sleep lab to titrate for flow limitation and expiratory pressure intolerance rather than only raising CPAP pressure.
  • Switch to bilevel or ASV when CPAP cannot normalize the expiratory airflow curve.
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