The Cell Danger Response and its Connection to Chronic Diseases

The podcast episode features an interview with Dr. Robert Navio, a renowned physician and researcher who specializes in mitochondrial medicine. Dr. Navio introduces the concept of the cell danger response (CDR), which is the body's natural biological reaction to stress, injury, infection, or threat. The CDR is responsible for triggering various physiological responses that aim to protect and heal the body. Dr. Navio explains that when the threat is slight, the CDR is confined to the affected tissues, but in severe cases or chronic illnesses, the CDR response can involve multiple systems and even affect the brain. Through metabolomic analysis of different complex disorders, Dr. Navio's research has identified dysregulated pathways related to the CDR in a range of chronic diseases, suggesting that these disorders share a common biological response.