1. Non-invasive vagus nerve stimulation as acute therapy for migraine: The randomized PRESTO study2. AAN 2018 Hot Topics plenary: Michael Wilson discusses metagenomics for diagnosing CNS infectionsDr. Teshamae Monteith talks with Dr. Cristina Tassorelli about her paper on vagus nerve stimulation for treating migraine, followed by a discussion with Dr. Stacey Clardy and Dr. Michael Wilson on next-generation sequencing and diagnosing meningitis and encephalitis. The second interview was originally recorded at the AAN Annual Meeting in Los Angeles.DISCLOSURES: Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH. Dr. Tassorelli has served on scientific advisory boards for Allergan Inc., ElectroCore LLC, Eli-Lilly and Company, Novartis, Teva Pharmaceutical Industries Ltd; has received funding for travel or speaker honoraria from Novartis, Allergan Inc, and Teva Pharmaceutical Industries Ltd; serves on editorial boards for Journal of Headache and Pain and Frontiers in Neurology; has consulted for Allergan Inc. and Eli Lilly and Company; has received research support from Eli Lilly and Company, Novartis, Teva Pharmaceuticals, ElectroCore, and the Italian Ministry of Health; and serves as Chairman of the Committee for the Guidelines of Clinical Trials of the International Headache Society. Dr. Clardy has received research support from Western Institute for Biomedical Research (WIBR). Dr. Wilson has received research support from NIH/National Center of Advancing Translational Science (NCATS), Clinical and Translational Science Institute (CTSI), and the American Brain Foundation Clinical Research Training Fellowship.