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Mitochondria play a vital role in energy production in cells. However, they also have a second role as environmental sensors, constantly sampling their environment and deciding how much energy to produce. They can shift between energy mode and defense mode, depending on the presence or absence of threats or stressors. The modern anti-hormetic lifestyle, which lacks challenging and stimulating stressors, leads to the shrinkage, shriveling, and atrophy of mitochondria. Mitochondrial biogenesis and exposure to hormetic stressors are essential for building bigger and stronger mitochondria. Increased mitochondrial capacity helps in adapting to and managing stress more efficiently, leading to improved energy levels and overall well-being.
Melatonin, often associated with sleep, is not just a hormone but also the most powerful antioxidant for mitochondria. It is produced not only in the brain but by mitochondria themselves. Melatonin helps protect mitochondria, neurons, and cells from damage and plays various vital roles, including preventing cancer. Chronic suppression of melatonin due to inadequate light exposure, especially at night, can lead to a melatonin deficiency, accumulation of damage, and negative health consequences. Red and near-infrared light exposure recharges melatonin stores and helps maintain redox balance, optimizing cellular and mitochondrial health.
Circadian rhythm, controlled by the central clock in the brain and peripheral clocks in various tissues, is crucial for regulating sleep-wake cycles, brain function, mood, and energy levels. Light is the primary input that controls the central clock, while nutrition greatly influences the peripheral clocks. Most people have desynchronized circadian rhythms due to extended exposure to artificial lighting and eating outside of a 12-hour window. Desynchronization leads to negative metabolic effects such as inflammation, mitochondrial dysfunction, insulin resistance, and hormonal dysregulation. Aligning the central and peripheral clocks through light exposure and time-restricted feeding promotes optimal energy regulation and overall health.
Reactive oxygen species (ROS) or oxidants, often viewed as harmful, actually play a vital signaling role. Under hormetic stress, transient increases in ROS notify mitochondria to grow bigger and stronger, leading to increased energy production. Antioxidants are crucial for maintaining the balance between oxidants and antioxidants, called redox balance. Supplementation with synthetic antioxidants like MitoQ and natural antioxidants like melatonin can penetrate mitochondria and reinforce their antioxidant defense system. Excessive antioxidant supplementation may interfere with hormetic stress and diminish the beneficial effects of stress on mitochondrial resilience.
Controlling your eating window, preferably between six to ten hours each day, can optimize circadian rhythm and improve metabolic health. Shortening the eating window gradually is recommended to allow for metabolic flexibility. Research suggests that early time restricted eating, starting the feeding window earlier in the day, supports better outcomes compared to later eating windows. By consuming more food earlier in the day, the body receives a signal that energy is abundant, leading to improved energy levels, increased fat loss, decreased oxidative stress, inflammation markers, and improved insulin sensitivity.
Taking steps to optimize mitochondrial function can have a significant impact on overall energy levels. Specific nutrients like acetyl-L-carnitine, Rhodiola rosea, astaxanthin, and NT Factor can support mitochondrial health, energy production, and recovery from exercise. Additionally, focusing on essential vitamins and minerals by using a premium multi-vitamin and mineral formula is crucial, as deficiencies in these nutrients are common. Building sustainable energy at the cellular level rather than relying on stimulants is key for long-term energy and vitality.
Today, I am blessed to have here with me the Founder of The Energy Blueprint, Ari Whitten. He is an energy and fatigue specialist who focuses on taking an evidence-based approach to energy enhancement, a nutrition, exercise, and natural health expert, and a #1 best-selling author.
He has been studying nutrition and holistic health for over two decades. He has a Bachelor of Science from San Diego State University in Kinesiology (specializing in fitness, nutrition, and health). He also has a background in exercise physiology and fitness and holds two advanced certifications from the National Academy of Sports Medicine as a Corrective Exercise Specialist and Performance Enhancement Specialist. In addition, he recently completed the three years of coursework for his Ph.D. in Clinical Psychology, an education which rounds out all aspects – nutrition, fitness, and psychology – of his approach to optimal health.
Ari is a tireless researcher who has obsessively devoted the last 20 years of his life to the pursuit of being on the cutting edge of the science of health and energy enhancement.
For the last six years, he’s been working with many of the top scientists and physicians on the planet to develop the most comprehensive program in the world on the science of overcoming fatigue and increasing energy — The Energy Blueprint.
In this episode, Ari first speaks about his Epstein Barr Virus diagnosis and how that took him down a rabbit hole of energy optimization. One way to improve chronic fatigue is by growing more mitochondria; Ari explains how this is possible. Then, Ari dives into melatonin and tips for fixing a circadian rhythm disruption. Tune in as we chat about the importance of hormetic stressors, Eat For Energy, and Ari’s products from The Energy Blueprint.
Purchase Ari’s new book Eat For Energy here: https://bit.ly/3Fka6VB
Join my upcoming FREE keto LIVE training here: http://www.ketosismasterclass.com
/ / E P I S O D E S P ON S O R S
PureForm Omega Plant Based Oils (Best Alternative to Fish Oil): http://www.purelifescience.com Use ben4 for $4.00 off.
Good Idea Functional Sparkling Water Drinks. Visit http://www.goodidea.us and use the coupon code BEN at checkout.
EveryDay Dose Everything you love about coffee, none of what you don't — say goodbye to jitters, anxiety, crash, and digestive issues. https://everydaydose.superfiliate.com/KETOKAMP (5 FREE Travel Packs + Free Frother applied)
Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list.
[00:45] Ari Speaks About Epstein Barr Virus and His Obsession With Energy Optimization
[08:45] The Key To Overcoming Fatigue Is Growing More Mitochondria
[17:50] Hormetic Stressors Will Make Your Mitochondria Bigger and Stronger
[27:30] Is Your Body Under Attack? Your Brain Will Create Sickness Behavior
[42:40] The Importance of Melatonin: What You Need To Know
[1:05:15] Ari Is Hypersensitive To Melatonin Supplements - Are You?
AND MUCH MORE!
Resources from this episode:
Watch Keto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ
Join my upcoming FREE keto LIVE training here: http://www.ketosismasterclass.com
/ / E P I S O D E S P ON S O R S
PureForm Omega Plant Based Oils (Best Alternative to Fish Oil): http://www.purelifescience.com Use ben4 for $4.00 off.
Good Idea Functional Sparkling Water Drinks. Visit http://www.goodidea.us and use the coupon code BEN at checkout.
EveryDay Dose Everything you love about coffee, none of what you don't — say goodbye to jitters, anxiety, crash, and digestive issues. https://everydaydose.superfiliate.com/KETOKAMP (5 FREE Travel Packs + Free Frother applied)
Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list.
*Some Links Are Affiliates*
// F O L L O W
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Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
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