

117 | Sean B. Carroll on Randomness and the Course of Evolution
6 snips Oct 5, 2020
Sean B. Carroll, a leading light in evolutionary developmental biology, dives into the messy world of evolution with rich insights. He discusses how randomness and chance play crucial roles, from genetic mutations to the larger evolutionary narrative. Carroll highlights the significance of regulatory genes and the interplay between adaptation and unpredictability. He also reflects on historical shifts in evolutionary theory, emphasizing that both chance and selection are essential to understanding life's complexity.
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Guest Introduction
- Sean B. Carroll, a renowned biologist, joins Sean Carroll on the Mindscape podcast.
- They discuss Carroll's work on evo-devo, the intersection of evolution and development.
Beyond Protein Coding
- DNA's role in development is more nuanced than just coding for proteins.
- It also regulates gene expression, crucial for cell differentiation and evolution.
Evo-Devo's Core Idea
- Evo-devo helps explain animal form diversity through development.
- A shared "genetic toolkit" builds bodies, prompting questions about differentiation.