1) The complexities of acute stroke decision-making and 2) Topic of the month: Living Legends Interviews. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Brett Kissela interviews Dr. Michel Shamy about his paper on the complexities of acute stroke decision-making. Dr. Roy Strowd is reading our e-Pearl of the week about Adie's tonic pupil. In the next part of the podcast Dr. Brett Kissela interviews Dr. Lou Caplan about his medical education and contributions to the field of neurology, interactions with C. Miller Fisher and advice to our younger listeners now beginning their careers. The participants had nothing to disclose except Drs. Kissela, Shamy, Strowd and Caplan.Dr. Kissela serves on scientific advisory board for Allergan, Inc.; has received funding for travel and speaker honoraria from Allergan, Inc.; has received research support from the NIH, will receive compensation from Reata Pharmaceuticals, Inc. for serving on the Event Adjudication Committee for the BEACON study, which they are sponsoring and provides medico-legal reviews.Dr. Shamy serves as an editorial board member of The Neurohospitalist; receives research support from Alberta Innovates Health Solutions Clinical Fellowship, H. Richard Tyler Award for Research in History of Neurology from the American Academy of Neurology.Dr. Strowd serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Caplan serves as an editorial board member of Archives of Neurology; serves as co-editor of Reviews in Neurological Diseases and receive payment for Aruba monitoring.