Joint Action Can a blood test predict the risk of osteoarthritis? A discussion with Dr Virginia Kraus
Mar 2, 2025
Dr. Virginia Kraus, a distinguished rheumatologist with over three decades of expertise in osteoarthritis research, joins the conversation to discuss groundbreaking blood tests that can predict osteoarthritis risk up to a decade in advance with 77% accuracy. She shares insights on the pivotal role of inflammation in the disease's progression and how early detection could revolutionize treatment strategies. The discussion also touches on the future of osteoarthritis diagnostics, emphasizing proactive health measures and ongoing research for better patient outcomes.
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Predicting Osteoarthritis
- A blood test can predict knee osteoarthritis risk 10 years in advance with 77% accuracy.
- This was shown in a study of women from the Chingford cohort, led by Dr. Virginia Kraus.
Early vs. Established OA
- Early osteoarthritis looks very similar to established, progressing osteoarthritis.
- This suggests that treatments for established osteoarthritis may be effective for early stages as well.
Sterile Wound Healing
- Osteoarthritis is a maladaptive, continuous wound healing response.
- The body continuously "cleans up" cartilage like the sorcerer's apprentice, eventually leading to cartilage loss.