11min chapter

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Can a blood test predict the risk of osteoarthritis? A discussion with Dr Virginia Kraus

Joint Action

CHAPTER

Predicting Osteoarthritis: The Blood Test Breakthrough

This chapter examines the innovative potential of a blood test to forecast an individual's risk of developing osteoarthritis. It discusses the implications of this predictive capability, the importance of proactive measures, and features insights from an expert on the disease's underlying mechanisms.

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Speaker 1
So it i gret
Speaker 2
elix om reading macen announcements and culporit moves that si rab's linkin to grow materially enough in ner future, both organically and inorganically. Kinny walker sto talk us through ther cringe acquisitionse that you just mentionp othat development and exploration. Ye.
Speaker 1
I mean, we are spending wen last year, being o the pandemic year, we just basely had to go into a sort of a little bit of himbernation. Weve we hadt cut op for back ain just a year of production from polito. We really had to park our exploration. We were going in to a very aggressive exploration plan around polito, because there's a lot of upsideing around polito. It's a plan constrained es. We know the plant needs to expand, and a satellite mine soll called saucheko. They both have amazing expiration upside a. Just to simply expand the polito plant blind would be silly. We trying to explore in and around that area to see maybe we should put some kind of small plant at sachek instead of expanding the polito plant either way, we need more plantpaplt, and the expiration effort is really ter and therefore there age we should do. So we've hadt postpone that for a year, but this year we're doing 30 thousand meters of drilling in round polito. We got four rigs there to day, drilling away, and we'll keep that going all this year and probably a big part of next year. So we're really throwing some dollars at the polito complex to actually push for organic growth and understand, you know, where, where, where we should best expand our plant, and by how much. Koringa is down the road from polito. It's a little too far away to actually have sort of, you know, production, any kind ofike operationor synegy in terms of feeding plant, ba, plant singy, for example. It's got ofvisly managerial and synegy, et cetera. But that's got its own plant a. It's, it's er. What we're doing at caringr is, we bought it in two thousand and 18 from anfield. We paid 22 million dollars in cash. That's all paid for. We paid for it out of a little bit of equity, rays but basily ad of cash flow. So we were. So cash flow from polito as basely bought off koringa. We're now busily er getting it ready for to start the mine. We've got the permit to start the underground mine at koringa now, so we plann to finally start our first blast in july. I'll be getting down there. Exciting time. See that mine begin. Be great. So we can spend the next sort of nine, 12 months developing the mind hard. That's, that's the issue with an underground mine. It's, it takes a tigtly tit. You've going to develop quite a lot of the underground, develop underground mine, before you start getting it set up ready to have a sustainable level of production. So like polito, there'll be a two year rampup to get the to get the mine started. Which means we do not have to start the process plan building it to morrow. We're still working and wet. You don't have the permit to start the the permit or to assemble the process plant yet. The permit plant is there, but it needs some but we're working through the last permit, what's clled th installation license. That's to allow us to assemble that plant, and ultimately switch it on. But again, that's not a long lead item, so we don't need to do that yet. But we hope to get that permit by the end of this year. We can aty start the sight clearance. And the e, the construction of the proces plant. But because the but about caringres we have the plant there already. We're not going out looking for it, to buy it or procure it. We we've already got the plant there. It's a second hand plant, but we're, we it'so really thee, the capexs am its civils, its concrete, its foundations. It's the the plumbing in the power, the electricity and all that stuff. And so e. So that the big part of our capex, that 25 milion odds is mine. Development is just basely getting under ground, initially with one heading, and then one heading can branch out into two headings. Two become four, four become eight, and we just go chasing er chasing veins underground all over the place. So we're that's all going to be a, that's what we can be doing over thenext sort of 18 months. So it's a underground development is the big push. And e starting in july. So that's e that' ats the plan.

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