The Fellow on Call: The Heme/Onc Podcast cover image

The Fellow on Call: The Heme/Onc Podcast

Episode 090: Prostate Cancer Series, Pt. 7- Treatment for Met. Castrate Resistant Prostate Cancer

Jan 24, 2024
In the final episode of the series on prostate cancer, they discuss the treatment options for metastatic castrate-resistant prostate cancer, including targeted agents like radium-223 and lutetium-177-PSMA-617. They also explore the role of PARP inhibitors in BRCA-mutated disease and the sequencing of different treatment options.
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Quick takeaways

  • Individualized treatment plans and consideration of quality of life are crucial for patients with metastatic castrate-resistant prostate cancer.
  • Testing for germline BRCA mutations and mismatch repair genes should be conducted in all patients with metastatic prostate cancer.

Deep dives

Newer therapies and critical appraisal in metastatic, castrate-resistant prostate cancer

In this episode, the hosts discuss the newer therapies and critical appraisal in metastatic, castrate-resistant prostate cancer. They highlight the importance of learning how to read research papers and evaluate treatment options. The limitations of some clinical trials are also mentioned, particularly in terms of control arm choices and sequencing of therapies. The hosts emphasize the need for individualized treatment plans and the consideration of quality of life for patients.

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