
Dr. Matt and Dr. Mike's Medical Podcast Q&A #11 - Reynaud's disease, fever physiology, and chronic stress and the immune system
Nov 15, 2025
The hosts dive into Raynaud's phenomenon, explaining its colorful symptoms and contrasting primary with secondary forms. They explore fascinating mechanisms behind vasospasm and discuss management strategies, including medication options. Fever takes the spotlight next, with insights into its role as a natural defense against infections and how the hypothalamus regulates body temperature. The conversation shifts to chronic stress, revealing its impact on immunity and metabolism, and how it mirrors the effects of steroids on the body.
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Episode notes
On-Camera Walk-On Mishap
- Mike recounts Matt accidentally walking into a live TV shoot and being told to get off stage.
- The story illustrates Matt's frequent absentminded, awkward moments during public events.
Wrong Door, Live Radio Interrupt
- Mike tells of Matt pressing the wrong studio door button and interrupting a live radio broadcast.
- The radio host reacted angrily and Matt shrugged it off, showing recurring social cluelessness.
Mistaken Passenger Door
- Mike describes Matt opening a stranger's car and startling the driver during a book tour.
- The incident reinforces Matt's pattern of being oblivious to surroundings while traveling.



