In this episode of Longevity By Design, Dr. Blander sits down with Dr. Mitch Roslin to discuss insulin resistance. Insulin resistance has been top of mind for Dr. Blander recently, and this conversation offers new insights into how we can prevent insulin resistance through diet and lifestyle. Dr. Roslin parses out the different factors that cause insulin resistance, explaining that some are within our control (diet and lifestyle) while others are not (age and genetics). Dr. Roslin also talks about his clinical experience as a bariatric surgeon, sharing insights on how to manage weight and prevent obesity. He gives his expertise on how to eat optimally for metabolic health and answers questions about the ketogenic diet and intermittent fasting.

Episode highlights:

Introduction: (0:00–2:45)
Insulin’s most important role in the body: (2:46–5:35)
What does it mean to be insulin resistant?: (5:35–7:15)
What causes insulin resistance?: (7:15–9:00)
Fasting insulin is an early warning sign for disease: (9:00–11:45)
Dr. Roslin’s clinical experience with obesity: (11:45–14:25)
Body fat is not a bad thing: (14:25–16:55)
Insulin levels impact where fat is stored in the body: (16:55–19:35)
How can we prevent insulin resistance?: (19:35–21:35)
Dr. Roslin’s thoughts on the ideal diet: (21:35–22:35)
Benefits of going for a walk after you eat: (22:35-23:55)
Diet vs. exercise for weight loss: (23:55–26:45)
Does the keto diet prevent insulin resistance? : (26:45–28:45)
Time-restricted eating for weight management: (28:45–33:15)
Psychology of obesity: (33:15–39:40)
Does insulin resistance make it harder to lose weight? (39:40–41:43)
What form of exercise is best to prevent insulin resistance? (41:43–46:05)
How do we objectively identify insulin resistance?: (46:05–48:30)
PCOS: (48:30–50:45)
Defining “healthy”: (50:45–52:45)
Wrap-up: (52:45-end)

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